|Product Name||Mouse C-Reactive Protein/CRP ELISA Kit|
|Customs Name||Mouse C-Reactive Protein/CRP ELISA Kit|
|Assay Type||Sandwich ELISA|
|Suitable Sample Type||serum, plasma, cell culture supernates|
|Format||96-well strip plate|
|Storage||4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)|
|Sample Volume||10 μl (prediluted)|
|Standard Curve Range||7.81 - 500 pg/ml|
|Spike Recovery Range||95%-106%|
|Mean Spike Recovery||101%|
|CV of Intra plate||3.9 % - 4.8 %|
|CV of Inter plate||3.6 % - 4.9 %|
|Components||96-well polystyrene microplate coated with a monoclonal antibody against CRP
Mouse CRP Standard, lyophilized
CRP Detect Antibody
Assay Buffer (10×)
Washing Buffer (20×)
|Describtion||This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse CRP. The Mouse C-Reactive Protein/CRP ELISA is for research use only. Not for diagnostic or therapeutic procedures.
C-reactive protein (CRP) is an annular (ring-shaped), pentameric protein found in blood plasma. CRP is synthesized by the liver in response to factors released by macrophages and fat cells (adipocytes). It is an acute-phase protein of hepatic origin that increases following interleukin-6 secretion by macrophages and T cells. Its physiological role is to bind to lysophosphatidylcholine expressed on the surface of dead or dying cells (and some types of bacteria) in order to activate the complement system via the C1Q complex. It is not related to C-peptide (insulin) or protein C (blood coagulation).
CRP is used mainly as a marker of inflammation, whose levels rise in response to inflammation. Recent research suggests that patients with elevated basal levels of CRP are at an increased risk of diabetes, hypertension and cardiovascular disease.