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MULTI SCIENCES

Mouse CXCL1/KC Enzyme Immunoassay Kit

Mouse CXCL1/KC Enzyme Immunoassay Kit

SKU:EK296

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Product Details

Mouse CXCL1/KC Enzyme Immunoassay Kit

Brand MultiSciences
CatNum 70-EK296
Product Name Mouse CXCL1/KC ELISA Kit
Customs Name Mouse CXCL1/KC ELISA Kit
Application ELISA
Reactivity Mouse
Assay Type Sandwich ELISA
Suitable Sample Type serum, plasma, cell culture supernates
Format 96-well strip plate
Storage 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition 4℃
Sample Volume 20 μl
Sensitivity 0.47 pg/ml
Standard Curve Range 31.25 - 2000 pg/ml
Spike Recovery Range 91 % - 107 %
Mean Spike Recovery 0.98
CV of Intra plate 3.9 % - 5.6 %
CV of Inter plate 4.4 % - 5.9 %
Components 96-well polystyrene microplate coated with a monoclonal antibody against CXCL1
Mouse CXCL1 Standard, lyophilized
CXCL1 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers
Describtion This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse CXCL1. The Mouse CXCL1/KC ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Chemokine (C-X-C motif) ligand 1 (CXCL1), also known as KC or N51, is a small cytokine belonging to the CXC chemokine family. It was originally identified in fibroblasts as a PDGF-induced immediate early gene that encodes a secretory protein of approximately 8 kDa.
CXCL1 is expressed by macrophages, neutrophils and epithelial cells, and has neutrophil chemoattractant activity. CXCL1 plays a role in spinal cord development by inhibiting the migration of oligodendrocyte precursors and is involved in the processes of angiogenesis, inflammation, wound healing, and tumorigenesis. CXCL1 is induced by inflammatory cytokines such as IL-1 and TNF, and IL-17A enhances expression of CXCL1 by prolonging the half-life of its constitutively unstable mRNA. An initial study in mice showed evidence that CXCL1 decreased the severity of multiple sclerosis and may offer a neuro-protective function.