96-well polystyrene microplate coated with a monoclonal antibody against Fetuin-A

Mouse Fetuin-A Standard, lyophilized

Fetuin-A Detect Antibody

Assay Buffer (10×)

Substrate (TMB)

Stop Solution

Washing Buffer (20×)

Plate Covers

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse Fetuin-A. The Mouse Fetuin-A/AHSG ELISA is for research use only. Not for diagnostic or therapeutic procedures.

Fetuins are blood proteins that are made in the liver and secreted into the bloodstream. They belong to a large group of binding proteins mediating the transport and availability of a wide variety of cargo substances in the bloodstream. Human fetuin is synonymous with α2-HS-glycoprotein (genetic symbol AHSG), α2-HS, A2HS, AHS, HSGA, and fetuin-A. Fetuin-A is regarded as a potent inhibitor of systemic calcification in gene knock-out mice. It has been demonstrated to play an important role in free fatty acid induced insulin resistance at liver. Fetuin-A is a predictor of adverse glycemic outcomes in pre-diabetes. It has been also been linked to increased occurrence of non-alcoholic fatty liver disease and cardiovascular events. It is a negative acute-phase reactant in sepsis and endotoxemia, promotes wound healing, and is neuroprotective in Alzheimer's disease. Decreased fetuin-A is a predictor of increased disease activity in obstructive lung disease, Crohn's disease, and ulcerative colitis