|Product Name||Mouse IL-16 ELISA Kit|
|Customs Name||Mouse IL-16 ELISA Kit|
|Assay Type||Sandwich ELISA|
|Suitable Sample Type||serum, plasma, cell culture supernates|
|Format||96-well strip plate|
|Storage||4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)|
|Sample Volume||10 μl|
|Standard Curve Range||7.81 - 500 pg/ml|
|Spike Recovery Range||91 % - 107 %|
|Mean Spike Recovery||0.98|
|CV of Intra plate||3.9 % - 5.6 %|
|CV of Inter plate||4.4 % - 5.9 %|
|Components||96-well polystyrene microplate coated with a monoclonal antibody against CXCL1
Mouse CXCL1 Standard, lyophilized
CXCL1 Detect Antibody
Assay Buffer (10×)
Washing Buffer (20×)
|Describtion||This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-16. The Mouse IL-16 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukin 16 (IL-16) is a cytokine that is released by a variety of cells (including lymphocytes and some epithelial cells) that has been characterized as a chemoattractant for certain immune cells expressing the cell surface molecule CD4. IL-16 was originally described as a factor that could attract activated T cells in humans, it was previously called lymphocyte chemoattractant factor (LCF). Since then, IL-16 has been shown to recruit and activate many other cells expressing the CD4 molecule, including monocytes, eosinophils, and dendritic cells. The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4.
IL-16 expression has been linked to inflammation processes in asthma, rheumatoid arthritis, systemic lupus erythematosus, colitis, atopic dermatitis, and multiple sclerosis. For example, the expression of IL-16 directly correlates with the number of infiltrating CD4+ T cells in asthmatic epithelium.