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MULTI SCIENCES

Mouse IL-16 Protein A ELISA Kit

Mouse IL-16 Protein A ELISA Kit

SKU:EK216

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Product Details

Mouse IL-16 Protein A ELISA Kit

Brand MultiSciences
CatNum 70-EK216
Product Name Mouse IL-16 ELISA Kit
Customs Name Mouse IL-16 ELISA Kit
Application ELISA
Reactivity Mouse
Assay Type Sandwich ELISA
Suitable Sample Type serum, plasma, cell culture supernates
Format 96-well strip plate
Storage 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition 4℃
Sample Volume 10 μl
Sensitivity 0.47 pg/ml
Standard Curve Range 7.81 - 500 pg/ml
Spike Recovery Range 91 % - 107 %
Mean Spike Recovery 0.98
CV of Intra plate 3.9 % - 5.6 %
CV of Inter plate 4.4 % - 5.9 %
Components 96-well polystyrene microplate coated with a monoclonal antibody against CXCL1
Mouse CXCL1 Standard, lyophilized
CXCL1 Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers
Describtion This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-16. The Mouse IL-16 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukin 16 (IL-16) is a cytokine that is released by a variety of cells (including lymphocytes and some epithelial cells) that has been characterized as a chemoattractant for certain immune cells expressing the cell surface molecule CD4. IL-16 was originally described as a factor that could attract activated T cells in humans, it was previously called lymphocyte chemoattractant factor (LCF). Since then, IL-16 has been shown to recruit and activate many other cells expressing the CD4 molecule, including monocytes, eosinophils, and dendritic cells. The protein encoded by this gene is a pleiotropic cytokine that functions as a chemoattractant, a modulator of T cell activation, and an inhibitor of HIV replication. The signaling process of this cytokine is mediated by CD4.
IL-16 expression has been linked to inflammation processes in asthma, rheumatoid arthritis, systemic lupus erythematosus, colitis, atopic dermatitis, and multiple sclerosis. For example, the expression of IL-16 directly correlates with the number of infiltrating CD4+ T cells in asthmatic epithelium.