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MULTI SCIENCES

Mouse IL-17A High Sensitivity Sandwich ELISA Kit

Mouse IL-17A High Sensitivity Sandwich ELISA Kit

SKU:EK217HS

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Product Details

Mouse IL-17A High Sensitivity Sandwich ELISA Kit

Factory Name

MultiSciences

CatNum

EK217HS

Product Name

Mouse IL-17A High Sensitivity ELISA Kit

Customs Name

Mouse IL-17A High Sensitivity ELISA Kit

SalePrice

$380

Application

ELISA

Reactivity

Mouse

SDS

SDS - EK217HS

Assay Type

Sandwich ELISA

Suitable Sample Type

serum, plasma, cell culture supernates

Format

96-well strip plate

Storage

4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)

Shipping Condition

4℃

Sample Volume

20 μl

Sensitivity

0.18 pg/ml

Standard Curve Range

1.56 - 100 pg/ml

Spike Recovery Range

82 % - 88 %

Mean Spike Recovery

85%

CV of Intra plate

4.1% - 4.9 %

CV of Inter plate

4.8 % - 9.7 %

Components

96-well polystyrene microplate coated with a monoclonal antibody against IL-17A

Mouse IL-17A Standard, lyophilized

IL-17A Detect Antibody

Standard Diluent

Streptavidin-HRP

Amplification Reagent Concentrate

Amplification Diluent

Assay Buffer (10×)

Substrate (TMB)

Stop Solution

Washing Buffer (20×)

Plate Covers

Describtion

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-17A. The Mouse IL-17A High Sensitivity ELISA is for research use only. Not for diagnostic or therapeutic procedures.

Interleukin 17 (IL-17) , also known as IL-17A and CTLA-8, is a homodimeric cytokine of about 32 kDa. IL-17 is a cytokine that acts as a potent mediator in delayed-type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation, similar to IFN-γ. IL-17 is produced by T-helper cells and is induced by IL-23 which results in destructive tissue damage in delayed-type reactions. IL-17 as a family functions as a proinflammatory cytokine that responds to the invasion of the immune system by extracellular pathogens and induces destruction of the pathogen’s cellular matrix. IL-17 acts synergistically with TNF and IL-1.

IL-17 family has been linked to many immune/autoimmune related diseases including rheumatoid arthritis, asthma, lupus, allograft rejection, anti-tumour immunity and recently Psoriasis.Increased levels of IL-17 have been associated with several conditions, including airway inflammation, rheumatoid arthritis, intraperitoneal abscesses and adhesions, inflammatory bowel disease, allograft rejection, psoriasis, cancer and multiple sclerosis.