MULTI SCIENCES
Mouse IL-17A High Sensitivity Sandwich ELISA Kit
Mouse IL-17A High Sensitivity Sandwich ELISA Kit
SKU:EK217HS
Product Details
Factory Name |
MultiSciences |
---|---|
CatNum |
EK217HS |
Product Name |
Mouse IL-17A High Sensitivity ELISA Kit |
Customs Name |
Mouse IL-17A High Sensitivity ELISA Kit |
SalePrice |
$380 |
Application |
ELISA |
Reactivity |
Mouse |
SDS |
SDS - EK217HS |
Assay Type |
Sandwich ELISA |
Suitable Sample Type |
serum, plasma, cell culture supernates |
Format |
96-well strip plate |
Storage |
4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened) |
Shipping Condition |
4℃ |
Sample Volume |
20 μl |
Sensitivity |
0.18 pg/ml |
Standard Curve Range |
1.56 - 100 pg/ml |
Spike Recovery Range |
82 % - 88 % |
Mean Spike Recovery |
85% |
CV of Intra plate |
4.1% - 4.9 % |
CV of Inter plate |
4.8 % - 9.7 % |
Components |
96-well polystyrene microplate coated with a monoclonal antibody against IL-17A Mouse IL-17A Standard, lyophilized IL-17A Detect Antibody Standard Diluent Streptavidin-HRP Amplification Reagent Concentrate Amplification Diluent Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
Describtion |
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-17A. The Mouse IL-17A High Sensitivity ELISA is for research use only. Not for diagnostic or therapeutic procedures. Interleukin 17 (IL-17) , also known as IL-17A and CTLA-8, is a homodimeric cytokine of about 32 kDa. IL-17 is a cytokine that acts as a potent mediator in delayed-type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation, similar to IFN-γ. IL-17 is produced by T-helper cells and is induced by IL-23 which results in destructive tissue damage in delayed-type reactions. IL-17 as a family functions as a proinflammatory cytokine that responds to the invasion of the immune system by extracellular pathogens and induces destruction of the pathogen’s cellular matrix. IL-17 acts synergistically with TNF and IL-1. IL-17 family has been linked to many immune/autoimmune related diseases including rheumatoid arthritis, asthma, lupus, allograft rejection, anti-tumour immunity and recently Psoriasis.Increased levels of IL-17 have been associated with several conditions, including airway inflammation, rheumatoid arthritis, intraperitoneal abscesses and adhesions, inflammatory bowel disease, allograft rejection, psoriasis, cancer and multiple sclerosis. |
