MULTI SCIENCES
Mouse IL-17AF Enzyme Immunoassay Kit
Mouse IL-17AF Enzyme Immunoassay Kit
SKU:EK21772
Product Details
Brand | MultiSciences |
---|---|
CatNum | 70-EK21772 |
Product Name | Mouse IL-17AF ELISA Kit |
Customs Name | Mouse IL-17AF ELISA Kit |
Application | ELISA |
Reactivity | Mouse |
Assay Type | Sandwich ELISA |
Suitable Sample Type | serum, plasma, cell culture supernates |
Format | 96-well strip plate |
Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
Shipping Condition | 4℃ |
Sample Volume | 20 μl |
Sensitivity | 4.54 pg/ml |
Standard Curve Range | 46.88 - 3000 pg/ml |
Spike Recovery Range | 73 % - 125 % |
Mean Spike Recovery | 1.1 |
CV of Intra plate | 4.4 % - 7.7 % |
CV of Inter plate | 4.7 % - 6.8 % |
Components | 96-well polystyrene microplate coated with a monoclonal antibody against IL-17AF Mouse IL-17AF Standard, lyophilized IL-17AF Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-17AF. The Mouse IL-17AF ELISA is for research use only. Not for diagnostic or therapeutic procedures. IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. Of the six IL-17 family members, IL-17A and IL-17F share the strongest homology (50% amino acid identity) and the two genes are located in the same chromosomal region. IL-17A and IL-17F have been observed in tissue samples from various autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, psoriasis, inflammatory bowel disease, and asthma. IL-17A expression is associated with many inflammatory diseases in humans, such as rheumatoid arthritis, multiple sclerosis, asthma, systemic lupus erythematosus, and allograft rejection. Expression of IL-17F is also linked with human inflammatory diseases, including asthma. |
