|Product Name||Mouse IL-17AF ELISA Kit|
|Customs Name||Mouse IL-17AF ELISA Kit|
|Assay Type||Sandwich ELISA|
|Suitable Sample Type||serum, plasma, cell culture supernates|
|Format||96-well strip plate|
|Storage||4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)|
|Sample Volume||20 μl|
|Standard Curve Range||46.88 - 3000 pg/ml|
|Spike Recovery Range||73 % - 125 %|
|Mean Spike Recovery||1.1|
|CV of Intra plate||4.4 % - 7.7 %|
|CV of Inter plate||4.7 % - 6.8 %|
|Components||96-well polystyrene microplate coated with a monoclonal antibody against IL-17AF
Mouse IL-17AF Standard, lyophilized
IL-17AF Detect Antibody
Assay Buffer (10×)
Washing Buffer (20×)
|Describtion||This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-17AF. The Mouse IL-17AF ELISA is for research use only. Not for diagnostic or therapeutic procedures.
IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. Of the six IL-17 family members, IL-17A and IL-17F share the strongest homology (50% amino acid identity) and the two genes are located in the same chromosomal region. IL-17A and IL-17F have been observed in tissue samples from various autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, psoriasis, inflammatory bowel disease, and asthma.
IL-17A expression is associated with many inflammatory diseases in humans, such as rheumatoid arthritis, multiple sclerosis, asthma, systemic lupus erythematosus, and allograft rejection. Expression of IL-17F is also linked with human inflammatory diseases, including asthma.