|Product Name||Mouse IL-17E/IL-25 ELISA Kit|
|Customs Name||Mouse IL-17E/IL-25 ELISA Kit|
|Assay Type||Sandwich ELISA|
|Suitable Sample Type||serum, plasma, cell culture supernates|
|Format||96-well strip plate|
|Storage||4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)|
|Sample Volume||10 μl|
|Standard Curve Range||62.50 - 4000 pg/ml|
|Spike Recovery Range||73 % - 99 %|
|Mean Spike Recovery||0.83|
|CV of Intra plate||3.2 % - 3.6 %|
|CV of Inter plate||3.8 % - 4.5 %|
|Components||96-well polystyrene microplate coated with a monoclonal antibody against IL-17E
Mouse IL-17E Standard, lyophilized
IL-17E Detect Antibody
Assay Buffer (10×)
Washing Buffer (20×)
|Describtion||This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-17E. The Mouse IL-17E/IL-25 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukin 17E (IL-17E), also known as IL-25, is a cytokine that belongs to the IL-17 cytokine family and is secreted by type 2 helper T cells (Th2) and mast cells. It shares the sequence similarity with IL-17. This cytokine can induce NF-κB activation, and stimulate the production of IL-8. Both this cytokine and IL-17B are ligands for the cytokine receptor IL-17RB. Studies in mice suggested that this cytokine may be a proinflammatory cytokine favoring Th2-type immune response.
IL-17E induces the production of other cytokines, including IL-4, IL-5 and IL-13 in multiple tissues, which stimulate the expansion of eosinophils. This cytokine is an important molecule controlling immunity of the gut and has been implicated in chronic inflammation associated with the gastrointestinal tract. IL-17E can kill some types of breast cancer cells.