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MULTI SCIENCES

Mouse IL-17F Assay ELISA Kit

Mouse IL-17F Assay ELISA Kit

SKU:EK2196

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Product Details

Mouse IL-17F Assay ELISA Kit

Brand MultiSciences
CatNum 70-EK2196
Product Name Mouse IL-17F ELISA Kit
Customs Name Mouse IL-17F ELISA Kit
Application ELISA
Reactivity Mouse
Assay Type Sandwich ELISA
Suitable Sample Type serum, plasma, cell culture supernates
Format 96-well strip plate
Storage 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition 4℃
Sample Volume 20 μl
Sensitivity 0.59 pg/ml
Standard Curve Range 31.25 - 2000 pg/ml
Spike Recovery Range 95 % - 112 %
Mean Spike Recovery 1.06
CV of Intra plate 2.9 % - 4.1 %
CV of Inter plate 3.3 % - 4.1 %
Components 96-well polystyrene microplate coated with a monoclonal antibody against IL-17F
Mouse IL-17F Standard, lyophilized
IL-17F Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers
Describtion This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-17F. The Mouse IL-17F ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukins 17F (IL-17F) and 17A (IL-17A) are closely related members of the IL-17 cytokine family, sharing about 50% amino acid identity. IL-17F is derived from several cell types such as Th17 cells, mast cells and basophils, and shows a wide tissue expression pattern including lung.
IL-17F is able to induce several cytokines, chemokines and adhesion molecules in bronchial epithelial cells, vein endothelial cells, fibroblasts and eosinophils. IL-17F utilizes IL-17RA and IL-17RC as its receptors, and activates the MAP kinase related pathway. Overexpression of IL-17F gene in the airway of mice is associated with airway neutrophilia, the induction of many cytokines, an increase in airway hyperreactivity, and mucus hypersecretion. Hence, IL-17F may have a crucial role in allergic airway inflammation, and have important therapeutic implications in asthma.