MULTI SCIENCES
Mouse IL-2 Antibody ELISA Kit
Mouse IL-2 Antibody ELISA Kit
SKU:EK202
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK202 |
| Product Name | Mouse IL-2 ELISA Kit |
| Customs Name | Mouse IL-2 ELISA Kit |
| Application | ELISA |
| Reactivity | Mouse |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 20 μl |
| Sensitivity | 0.54 pg/ml |
| Standard Curve Range | 7.81 - 500 pg/ml |
| Spike Recovery Range | 93 % - 113 % |
| Mean Spike Recovery | 100% |
| CV of Intra plate | 5.1 % - 9.0 % |
| CV of Inter plate | 3.3 % - 6.0 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against Mouse IL-2 Mouse IL-2 Standard, lyophilized Mouse IL-2 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-2. The Mouse IL-2 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Interleukin-2 (IL-2) is a 15-16 kDa monomeric, α-helical glycoprotein that belongs to the Type I cytokine family. Mouse IL-2 is synthesized as a 169 amino acid (aa) precursor that contains a 20 aa signal sequence and a 149 aa mature chain, and mature mouse IL-2 shares 56% and 73% aa sequence identity with mature human and rat IL-2. IL-2 is part of the body's natural response to microbial infection, and in discriminating between foreign ("non-self") and "self". IL-2 has key roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells. IL-2 also promotes the differentiation of T cells into effector T cells and into memory T cells when the initial T cells is also stimulated by an antigen, thus helping the body fight off infections. Monitoring of IL-2 levels in serum provides more detailed insights in several pathological situations such as cancer, infectious diseases, transplant rejection, multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus and type I diabetes. |
