|Product Name||Mouse IL-2 High Sensitivity ELISA Kit|
|Customs Name||Mouse IL-2 High Sensitivity ELISA Kit|
|Product Spec||96 T|
|Assay Type||Sandwich ELISA|
|Suitable Sample Type||serum, plasma, cell culture supernates|
|Format||96-well strip plate|
|Storage||4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)|
|Sample Volume||20 μl|
|Standard Curve Range||0.23 - 15 pg/ml|
|Spike Recovery Range||82 % - 98 %|
|Mean Spike Recovery||92%|
|CV of Intra plate||4.5 % - 4.9 %|
|CV of Inter plate||4.4 % - 8.9 %|
|Components||96-well polystyrene microplate coated with a monoclonal antibody against IL-2
Mouse IL-2 Standard, lyophilized
IL-2 Detect Antibody
Amplification Reagent Concentrate
Assay Buffer (10×)
Washing Buffer (20×)
|Describtion||This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-2. The Mouse IL-2 High Sensitivity ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukin-2 (IL-2) is a 15-16 kDa monomeric, α-helical glycoprotein that belongs to the Type I cytokine family. Mouse IL-2 is synthesized as a 169 amino acid (aa) precursor that contains a 20 aa signal sequence and a 149 aa mature chain, and mature mouse IL-2 shares 56% and 73% aa sequence identity with mature human and rat IL-2. IL-2 is part of the body's natural response to microbial infection, and in discriminating between foreign ("non-self") and "self". IL-2 has key roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells. IL-2 also promotes the differentiation of T cells into effector T cells and into memory T cells when the initial T cells is also stimulated by an antigen, thus helping the body fight off infections.
Monitoring of IL-2 levels in serum provides more detailed insights in several pathological situations such as cancer, infectious diseases, transplant rejection, multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus and type I diabetes.