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MULTI SCIENCES

Mouse IL-2 High Sensitivity ELISA Kit Dsitributor

Mouse IL-2 High Sensitivity ELISA Kit Dsitributor

SKU:EK202HS

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Mouse IL-2 High Sensitivity ELISA Kit Dsitributor

Factory Name MultiSciences
CatNum EK202HS
Product Name Mouse IL-2 High  Sensitivity ELISA Kit
Customs Name Mouse IL-2 High  Sensitivity ELISA Kit
Product Spec 96 T
Application ELISA
Reactivity Mouse
Assay Type Sandwich ELISA
Suitable  Sample Type serum, plasma, cell  culture supernates
Format 96-well strip plate
Storage 4℃ (unopened)standard  stored at -20℃, others stored at 4℃ (opened)
Shipping  Condition 4℃
Sample Volume 20 μl
Sensitivity 0.05 pg/ml
Standard Curve  Range 0.23 - 15 pg/ml
Spike Recovery  Range 82 % - 98 %
Mean Spike  Recovery 92%
CV of Intra  plate 4.5 % - 4.9 %
CV of Inter  plate 4.4 % - 8.9 %
Components 96-well polystyrene  microplate coated with a monoclonal antibody against IL-2
Mouse IL-2 Standard, lyophilized
IL-2 Detect Antibody
Standard Diluent
Streptavidin-HRP
Amplification Reagent Concentrate
Amplification Diluent
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers
Describtion This assay employs  the quantitative sandwich enzyme immunoassay technique for the quantitative  detection of mouse IL-2. The Mouse IL-2 High Sensitivity ELISA is for research use only. Not for  diagnostic or therapeutic procedures.
Interleukin-2 (IL-2) is a 15-16 kDa monomeric, α-helical glycoprotein that  belongs to the Type I cytokine family. Mouse IL-2 is synthesized as a 169  amino acid (aa) precursor that contains a 20 aa signal sequence and a 149 aa  mature chain, and mature mouse IL-2 shares 56% and 73% aa sequence identity  with mature human and rat IL-2. IL-2 is part of the body's natural response  to microbial infection, and in discriminating between foreign  ("non-self") and "self". IL-2 has key roles in key  functions of the immune system, tolerance and immunity, primarily via its  direct effects on T cells. IL-2 also promotes the differentiation of T cells  into effector T cells and into memory T cells when the initial T cells is also  stimulated by an antigen, thus helping the body fight off infections.
Monitoring of IL-2 levels in serum provides more detailed insights in  several pathological situations such as cancer, infectious diseases,  transplant rejection, multiple sclerosis, rheumatoid arthritis, systemic  lupus erythematosus and type I diabetes.