MULTI SCIENCES
Mouse IL-21 ELISA Kit Distributor
Mouse IL-21 ELISA Kit Distributor
SKU:EK221
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK221 |
| Product Name | Mouse IL-21 ELISA Kit |
| Customs Name | Mouse IL-21 ELISA Kit |
| Application | ELISA |
| Reactivity | Mouse |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 10 μl |
| Sensitivity | 0.58 pg/ml |
| Standard Curve Range | 31.25 - 2000 pg/ml |
| Spike Recovery Range | 85 % - 114 % |
| Mean Spike Recovery | 0.96 |
| CV of Intra plate | 3.0 % - 5.5 % |
| CV of Inter plate | 3.5 % - 6.1 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against IL-21 Mouse IL-21 Standard, lyophilized IL-21 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse 21. The Mouse IL-21 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Interleukin-21 (IL-21) is a cytokine that has potent regulatory effects on cells of the immune system, including natural killer (NK) cells and cytotoxic T cells that can destroy virally infected or cancerous cells. This cytokine induces cell division/proliferation in its target cells. IL-21 is expressed in activated human CD4+ T cells but not in most other tissues. In addition, IL-21 expression is up-regulated in Th2 and Th17 subsets of T helper cells, as well as T follicular cells. Furthermore IL-21 is expressed in NK T cells regulating the function of these cells. IL-21 has pathologic function in immune-inflammatory diseases. Data suggest the existence of a positive autocrine loop that could help to amplify and stabilize IL-21-driven, T cell-mediated responses. Moreover, it has antitumour activity and may have a role in the development of autoimmunity. IL-21 may have therapeutic potentials as an antitumor agent in the clinic. |
