MULTI SCIENCES
Mouse IL-23 ELISA Kit Distributor
Mouse IL-23 ELISA Kit Distributor
SKU:EK223
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK223 |
| Product Name | Mouse IL-23 ELISA Kit |
| Customs Name | Mouse IL-23 ELISA Kit |
| Application | ELISA |
| Reactivity | Mouse |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 20 μl |
| Sensitivity | 3.36 pg/ml |
| Standard Curve Range | 1.56 - 100 pg/ml |
| Spike Recovery Range | 83 % - 117 % |
| Mean Spike Recovery | 0.99 |
| CV of Intra plate | 2.0 % - 5.3 % |
| CV of Inter plate | 4.1 % - 6.0 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against TGF-β1 Mouse TGF-β1 Standard, lyophilized TGF-β1 Detect Antibody Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution washing Buffer (20×) HCl NaOH Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-23. The Mouse IL-23 ELISA is for research use only. Not for diagnostic or therapeutic procedures. IL-23 protein is a heterodimer, sharing a p40 subunit with IL-12, but having a distinct p19 subunit, which is IL-23 specific. Prior to the discovery of IL-23, IL-12 had been proposed to represent a key mediator of inflammation in mouse models of inflammation. However, many studies aimed at assessing the role of IL-12 had blocked the activity of IL-12p40, and were therefore not as specific as thought. Studies which blocked the function of IL-12p35 did not produce the same results as those targeting IL-12p40 as would have been expected if both subunits formed part of IL-12 only. IL-23 was shown to be involved in inflammation of the nervous system and autoimmune diseases. IL-23 was shown to facilitate development of inflammation in numerous other models of immune pathology where IL-12 had previously been implicated including models of arthritis, intestinal inflammation, and psoriasis. |
