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MULTI SCIENCES

Mouse IL-5 High Sensitivity Antibody ELISA Kit

Mouse IL-5 High Sensitivity Antibody ELISA Kit

SKU:EK205HS

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Product Details

Mouse IL-5 High Sensitivity Antibody ELISA Kit

Factory Name

MultiSciences

CatNum

EK205HS

Product Name

Mouse IL-5 High Sensitivity ELISA Kit

Customs Name

Mouse IL-5 High Sensitivity ELISA Kit

SalePrice

$380

Application

ELISA

Reactivity

Mouse

SDS

SDS - EK205HS

Assay Type

Sandwich ELISA

Suitable Sample Type

serum, plasma, cell culture supernates

Format

96-well strip plate

Storage

4℃ (unopened)standard stored at -20℃, others stored at 4℃ (opened)

Shipping Condition

4℃

Sample Volume

20 μl

Sensitivity

0.14 pg/ml

Standard Curve Range

1.56 - 100 pg/ml

Spike Recovery Range

104 % - 107 %

Mean Spike Recovery

105%

CV of Intra plate

4.8 % - 5.0 %

CV of Inter plate

3.0 % - 5.3 %

Release Date

2017-9-6

Components

96-well polystyrene microplate coated with a monoclonal antibody against IL-5

Mouse IL-5 Standard, lyophilized

IL-5 Detect Antibody

Standard Diluent

Streptavidin-HRP

Amplification Reagent Concentrate

Amplification Diluent

Assay Buffer (10×)

Substrate (TMB)

Stop Solution

Washing Buffer (20×)

Plate Covers

Describtion

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-5. The Mouse IL-5 High Sensitivity ELISA is for research use only. Not for diagnostic or therapeutic procedures. IL-5 is a 115-amino acid-long Th2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely IL-3 and GM-CSF), this glycoprotein in its active form is a homodimer. IL-5 is produced by Th2 cells and mast cells. The spectrum of biological

activities of IL-5, on B cells as well as other cell types suggests that IL-5 plays an important functional role in the activities of Th2 cells. Through binding to the IL-5 receptor, IL-5 stimulates B cell growth and increases immunoglobulin secretion. It is also a key mediator in eosinophil activation.

IL-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma, wherein a large increase in the number of circulating, airway tissue, and induced sputum eosinophils have been observed.