|Product Name||Mouse IL-6 ELISA Kit|
|Customs Name||Mouse IL-6 ELISA Kit|
|Assay Type||Sandwich ELISA|
|Suitable Sample Type||serum, plasma, cell culture supernates|
|Format||96-well strip plate|
|Storage||4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)|
|Sample Volume||20 μl|
|Standard Curve Range||15.63 - 1000 pg/ml|
|Spike Recovery Range||89 % - 112 %|
|Mean Spike Recovery||1.02|
|CV of Intra plate||2.1 % - 5.3 %|
|CV of Inter plate||2.3 % - 3.0 %|
|Components||96-well polystyrene microplate coated with a monoclonal antibody against Mouse IL-6
Mouse IL-6 Standard, lyophilized
Mouse IL-6 Detect Antibody
Assay Buffer (10×)
washing Buffer (20×)
|Describtion||This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IL-6. The Mouse IL-6 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukin 6 (IL-6) is an interleukin that acts as both a pro-inflammatory cytokine and an anti-inflammatory myokine. Mature mouse IL-6 is 187 amino acids (aa) in length and shares 39% and 85% aa sequence identity with human and rat IL-6.
IL-6 is secreted by T cells and macrophages to stimulate immune response, e.g. during infection and after trauma, especially burns or other tissue damage leading to inflammation. IL-6 also plays a role in fighting infection, as IL-6 has been shown in mice to be required for resistance against bacteriumStreptococcus pneumoniae.
IL-6 stimulates the inflammatory and auto-immune processes in many diseases such as diabetes, atherosclerosis, depression, Alzheimer's Disease, systemic lupus erythematosus, multiple myeloma, prostate cancer, Beh?et's disease, and rheumatoid arthritis. Advanced/ metastatic cancer patients have higher levels of IL-6 in their blood.