MULTI SCIENCES
Mouse Myeloperoxidase/MPO Antibody ELISA Kit
Mouse Myeloperoxidase/MPO Antibody ELISA Kit
SKU:EK2133
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK2133 |
| Product Name | Mouse myeloperoxidase/MPO ELISA Kit |
| Customs Name | Mouse myeloperoxidase/MPO ELISA Kit |
| Application | ELISA |
| Reactivity | Mouse |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 20 μl (prediluted) |
| Sensitivity | 4.40 pg/ml |
| Standard Curve Range | 62.50 - 4000 pg/ml |
| Spike Recovery Range | 91 % - 107 % |
| Mean Spike Recovery | 0.99 |
| CV of Intra plate | 3.8 % - 5.4 % |
| CV of Inter plate | 3.0 % - 4.1 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against MPO Mouse MPO Standard, lyophilized MPO Detect Antibody Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse MPO. The Mouse myeloperoxidase/MPO ELISA is for research use only. Not for diagnostic or therapeutic procedures. Myeloperoxidase (MPO) is a peroxidase enzyme most abundantly expressed in neutrophil granulocytes, and produces hypohalous acids to carry out their antimicrobial activity. MPO oxidation of apoA-I reduces HDL-mediated inhibition of apoptosis and inflammation. MPO mediates protein nitrosylation and the formation of 3-chlorotyrosine and dityrosine crosslinks. MPO deficiency is a hereditary deficiency of the enzyme, which predisposes to immune deficiency. Studies have reported an association between elevated MPO levels and the severity of coronary artery disease. It has also been suggested that MPO plays a significant role in the development of the atherosclerotic lesion and rendering plaques unstable. |
