MULTI SCIENCES
Mouse/Rat IGF-1 ELISA Kit Distributor
Mouse/Rat IGF-1 ELISA Kit Distributor
SKU:EK9131
Product Details
| CatNum | 70-EK9131 |
|---|---|
| Product Name | Mouse/Rat IGF-1 ELISA Kit |
| Customs Name | Mouse/Rat IGF-1 ELISA Kit |
| Application | ELISA |
| Reactivity | Mouse/Rat |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 100 μl (prediluted) |
| Sensitivity | 0.82 pg/ml |
| Standard Curve Range | 15.63 - 1000 pg/ml |
| Spike Recovery Range | 95%-110% |
| Mean Spike Recovery | 102% |
| CV of Intra plate | 2.9 % - 3.6 % |
| CV of Inter plate | 2.0 % - 4.1 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against IGF-1 Mouse/Rat IGF-1 Standard, lyophilized IGF-1 Detect Antibody Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse and rat IGF-1. The Mouse/Rat IGF-1 ELISA is for research use only. Not for diagnostic or therapeutic procedures. Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin. It is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. IGF-1 is one of the most potent natural activators of the AKT signaling pathway, a stimulator of cell growth and proliferation, and a potent inhibitor of programmed cell death. IGF-1 binds to at least two cell surface receptors: the IGF-1 receptor (IGF1R), and the insulin receptor. IGF-1 production is stimulated by growth hormone and can be retarded by undernutrition, growth hormone insensitivity, lack of growth hormone receptors, or failures of the downstream signalling pathway post growth hormone receptor including SHP2 and STAT5B. IGF-1 plays an important role in childhood growth and continues to have anabolic effects in adults. It is also related to aging, neuropathy, cancer and stroke. |
