MULTI SCIENCES
Mouse ST2/IL-33R Protein A ELISA Kit
Mouse ST2/IL-33R Protein A ELISA Kit
SKU:EK2163
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK2163 |
| Product Name | Mouse ST2/IL-33R ELISA Kit |
| Customs Name | Mouse ST2/IL-33R ELISA Kit |
| Application | ELISA |
| Reactivity | Mouse |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 10 μl |
| Sensitivity | 0.27 pg/ml |
| Standard Curve Range | 62.50 - 4000 pg/ml |
| Spike Recovery Range | 83%-116% |
| Mean Spike Recovery | 102% |
| CV of Intra plate | 3.9 % - 4.8 % |
| CV of Inter plate | 3.6 % - 4.9 % |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against CRP Mouse CRP Standard, lyophilized CRP Detect Antibody Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse ST2. The Mouse ST2/IL-33R ELISA is for research use only. Not for diagnostic or therapeutic procedures. Suppression of Tumorigenicity 2 (ST2), also known as IL-33R, is an Interleukin-1 receptor family glycoprotein that contributes to Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes. ST2 binds IL-33, a pro-inflammatory IL-1 family cytokine with intracellular and extracellular activities. In addition to its role in promoting mast cell and Th2 dependent inflammation, transmembrane ST2 activation enhances inflammation-associated hypernociception and protects from atherosclerosis and cardiac myocyte hypertrophy. The soluble ST2 isoform is elevated in the serum under inflammatory conditions including allergic asthma, sepsis, trauma, dengue fever, and pulmonary disease. Serum ST2 elevation is also associated with multiple aspects of heart failure including aortic stenosis, congestive cardiomyopathy, and risk of cardiovascular heart failure and death. |
