MultiSciences

70-EK380HS

EK380HS

Rat IFN-γ High Sensitivity ELISA Kit

Rat IFN-γ High Sensitivity ELISA Kit

96 T

ELISA

Rat

SDS - EK380HS

Sandwich ELISA

serum, plasma, cell culture supernates

96-well strip plate

4℃ (unopened)standard stored at -20℃, others  stored at 4℃ (opened)

4℃

20 μl

0.26 pg/ml

3.13 - 200 pg/ml

73 % - 137 %

0.93

3.7 % - 4.4 %

2.4 % - 8.5 %

43019

96-well polystyrene microplate coated with  a monoclonal antibody against IFN-γ
Rat IFN-γ Standard, lyophilized
IFN-γ Detect Antibody
Standard Diluent
Streptavidin-HRP
Amplification Reagent Concentrate
Amplification Diluent
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of rat IFN-γ. The Rat IFN-γ ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interferon gamma (IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. IFN-γ, or type II interferon, is a cytokine that is critical forinnate and adaptive immunity against viral, some bacterial and protozoal infections. IFN-γ is an important activator of macrophages and inducer of Class II major histocompatibility complex (MHC) molecule expression. Aberrant IFN-γ expression is associated with a number of autoinflammatory and  autoimmunediseases. The importance of IFN-γ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFN-γ is produced  predominantly by natural killer (NK) and natural killer T (NKT) cells as part  of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocyte  (CTL) effector T cells onceantigen- specific immunity develops.
The role of IFN-γ as a disease marker has been demonstrated for a number of different pathological situations including infections, autoimmune diseases, transplant rejection, allergy and diabetes.