MULTI SCIENCES
Rat IL-17A Sandwich ELISA Kit
Rat IL-17A Sandwich ELISA Kit
SKU:EK317
Product Details
| Brand | MultiSciences |
|---|---|
| CatNum | 70-EK317 |
| Product Name | Rat IL-17A ELISA Kit |
| Customs Name | Rat IL-17A ELISA Kit |
| Application | ELISA |
| Reactivity | Rat |
| Assay Type | Sandwich ELISA |
| Suitable Sample Type | serum, plasma, cell culture supernates |
| Format | 96-well strip plate |
| Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
| Shipping Condition | 4℃ |
| Sample Volume | 10 μl |
| Sensitivity | 0.62 pg/ml |
| Standard Curve Range | 3.13 - 200 pg/ml |
| Spike Recovery Range | 94 % - 119 % |
| Mean Spike Recovery | 1.03 |
| CV of Intra plate | 3.9 % - 7.1 % |
| CV of Inter plate | 3.0 % - 3.9 % |
| Release Date | 2016/8/20 |
| Components | 96-well polystyrene microplate coated with a monoclonal antibody against IL-17A Rat IL-17A Standard, lyophilized IL-17A Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
| Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of rat IL-17A. The Rat IL-17A ELISA is for research use only. Not for use in therapeutic procedures. IL-17, also known as IL-17A and CTLA-8, is a homodimeric cytokine of about 32 kDa. IL-17 is a cytokine that acts as a potent mediator in delayed-type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation, similar to IFN-γ. IL-17 is produced by T-helper cells and is induced by IL-23 which results in destructive tissue damage in delayed-type reactions. IL-17 as a family functions as a proinflammatory cytokine that responds to the invasion of the immune system by extracellular pathogens and induces destruction of the pathogen's cellular matrix. IL-17 acts synergistically with TNF and IL-1. IL-17 family has been linked to many immune / autoimmune related diseases including rheumatoid arthritis, asthma, lupus, allograft rejection, anti-tumour immunity and recently Psoriasis.Increased levels of IL-17 have been associated with several conditions, including airway inflammation, rheumatoid arthritis, intraperitoneal abscesses and adhesions, inflammatory bowel disease, allograft rejection, psoriasis, cancer and multiple sclerosis. |
