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MULTI SCIENCES

Rat IL-17A Sandwich ELISA Kit

Rat IL-17A Sandwich ELISA Kit

SKU:EK317

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Product Details

Rat IL-17A Sandwich ELISA Kit

Brand MultiSciences
CatNum 70-EK317
Product Name Rat IL-17A ELISA Kit
Customs Name Rat IL-17A ELISA Kit
Application ELISA
Reactivity Rat
Assay Type Sandwich ELISA
Suitable Sample Type serum, plasma, cell culture supernates
Format 96-well strip plate
Storage 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)
Shipping Condition 4℃
Sample Volume 10 μl
Sensitivity 0.62 pg/ml
Standard Curve Range 3.13 - 200 pg/ml
Spike Recovery Range 94 % - 119 %
Mean Spike Recovery 1.03
CV of Intra plate 3.9 % - 7.1 %
CV of Inter plate 3.0 % - 3.9 %
Release Date 2016/8/20
Components 96-well polystyrene microplate coated with a monoclonal antibody against IL-17A
Rat IL-17A Standard, lyophilized
IL-17A Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10×)
Substrate (TMB)
Stop Solution
Washing Buffer (20×)
Plate Covers
Describtion This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of rat IL-17A. The Rat IL-17A ELISA is for research use only. Not for use in therapeutic procedures.
IL-17, also known as IL-17A and CTLA-8, is a homodimeric cytokine of about 32 kDa. IL-17 is a cytokine that acts as a potent mediator in delayed-type reactions by increasing chemokine production in various tissues to recruit monocytes and neutrophils to the site of inflammation, similar to IFN-γ. IL-17 is produced by T-helper cells and is induced by IL-23 which results in destructive tissue damage in delayed-type reactions. IL-17 as a family functions as a proinflammatory cytokine that responds to the invasion of the immune system by extracellular pathogens and induces destruction of the pathogen's cellular matrix. IL-17 acts synergistically with TNF and IL-1.
IL-17 family has been linked to many immune / autoimmune related diseases including rheumatoid arthritis, asthma, lupus, allograft rejection, anti-tumour immunity and recently Psoriasis.Increased levels of IL-17 have been associated with several conditions, including airway inflammation, rheumatoid arthritis, intraperitoneal abscesses and adhesions, inflammatory bowel disease, allograft rejection, psoriasis, cancer and multiple sclerosis.