|Product Name||Rat IL-2 ELISA Kit|
|Customs Name||Rat IL-2 ELISA Kit|
|Assay Type||Sandwich ELISA|
|Suitable Sample Type||serum, plasma, cell culture supernates|
|Format||96-well strip plate|
|Storage||4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened)|
|Sample Volume||20 μl|
|Standard Curve Range||31.25 - 2000 pg/ml|
|Spike Recovery Range||85 % - 110 %|
|Mean Spike Recovery||1.02|
|CV of Intra plate||3.5 % - 6.8 %|
|CV of Inter plate||5.5 % - 8.2 %|
|Components||96-well polystyrene microplate coated with a monoclonal antibody against IL-2
Rat IL-2 Standard, lyophilized
IL-2 Detect Antibody
Assay Buffer (10×)
washing Buffer (20×)
|Describtion||This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of rat IL-2. The Rat IL-2 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
Interleukin 2 (IL-2) is a 15 kDa glycoprotein encoded by a single gene located in the q26-28 region of human chromosome 4. It is a type of cytokine signaling molecule in the immune system, regulating the activities of white blood cells (leukocytes, often lymphocytes) responsible for immunity. IL-2 is part of the body's natural response to microbial infection, and in discriminating between foreign ("non-self") and "self". IL-2 mediates its effects by binding to IL-2 receptors, a complex consisting of three chains, termed α (CD25), β (CD122) and γ (CD132).
Monitoring of IL-2 levels in serum provides more detailed insights in several pathological situations such as cancer, infectious diseases, transplant rejection, multiple sclerosis, rheumatoid arthritis, systemic lupus erythematosus and type I diabetes.