MULTI SCIENCES
RUO Human CXCL5/ENA-78 ELISA Kit
RUO Human CXCL5/ENA-78 ELISA Kit
SKU:EK1219
Product Details
Brand | MultiSciences |
---|---|
CatNum | 70-EK1219 |
Product Name | Human CXCL5/ENA-78 ELISA Kit |
Customs Name | Human CXCL5/ENA-78 ELISA Kit |
Application | ELISA |
Reactivity | Human |
Assay Type | Sandwich ELISA |
Suitable Sample Type | serum, plasma, cell culture supernates |
Format | 96-well strip plate |
Storage | 4℃ (unopened) standard stored at -20℃, others stored at 4℃ (opened) |
Shipping Condition | 4℃ |
Sample Volume | 10 μl |
Sensitivity | 13.45 pg/ml |
Standard Curve Range | 31.25 - 2000 pg/ml |
Spike Recovery Range | 82 % - 125 % |
Mean Spike Recovery | 1.01 |
CV of Intra plate | 4.9 % - 6.4 % |
CV of Inter plate | 2.8 % - 3.9 % |
Components | 96-well polystyrene microplate coated with a monoclonal antibody against CXCL5 Human CXCL5 Standard, lyophilized CXCL5 Detect Antibody Standard Diluent Streptavidin-HRP Assay Buffer (10×) Substrate (TMB) Stop Solution Washing Buffer (20×) Plate Covers |
Describtion | This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human CXCL5. The Human CXCL5/ENA-78 ELISA is for research use only. Not for diagnostic or therapeutic procedures. C-X-C motif chemokine 5 (CXCL5), also known as epithelial-derived neutrophil-activating peptide 78 (ENA-78), is a small cytokine belonging to the CXC chemokine family. It is produced following stimulation of cells with the inflammatory cytokines IL-1 or TNF-α. Expression of CXCL5 has also been observed in eosinophils, and can be inhibited with the type II interferon IFN-γ. CXCL5 elicits these effects by interacting with the cell surface chemokine receptor CXCR2. It stimulates the chemotaxis of neutrophils possessing angiogenic properties and has been implicated in connective tissue remodelling. CXCL5 has been also described to regulate neutrophil homeostasis. CXCL5 expression is higher in atherosclerosis (a chronic inflammatory condition) but is not associated with neutrophil infiltration. Instead CXCL5 has a protective role in atherosclerosis by directly controlling macrophage foam cell formation. |
