Product Category
Newest Products
Human uPAR ELISA Kit
$350.00 – $450.00
| Sample Type | Serum, plasma, cell culture supernatant, and other biological samples |
|---|---|
| Sample Volume | 10 μL |
| Sensitivity | 0.87 pg/mL |
| Range | 62.5 pg/mL – 4000 pg/mL |
| Assay Time | 3.5 h |
| Recovery | 87% – 114% |
| Average Recovery | 1.01 |
| Intra Precision | 3.0% – 4.7% |
| Inter-Precision | 2.1% – 5.0% |
| Platform | ELISA |
| Plate | Detachable 96-well plate |
| Size | 96T/48T |
| Storage | If the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard solution should be stored at -20℃, while the other components should be stored at 4℃. |
| Delivery | 4℃ blue ice transportation |
| Components | 96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-uPAR monoclonal antibody Human uPAR freeze-dried standard uPAR detect Antibody Standard Diluent Assay Buffer(10×) Substrate TMB Stop Solution Washing Buffer(20×) Sealing Film |
| Assay Principle | This kit utilizes the double antibody sandwich enzyme-linked immunosorbent assay (ELISA) detection technique.Specific anti-human uPAR antibodies are precoated on a high-affinity ELISA plate. Standard samples, test samples, and biotinylated detection antibodies are added to the wells of the ELISA plate. After incubation, uPAR present in the samples binds to the solid-phase antibodies and the detection antibodies. After washing to remove unbound substances, streptavidin-HRP labeled with horseradish peroxidase is added. After washing, a colorimetric substrate, TMB, is added and the plate is incubated in the dark for color development. The intensity of the color reaction is directly proportional to the concentration of uPAR in the samples.A stop solution is added to terminate the reaction, and the absorbance value is measured at a wavelength of 450 nm (with a reference wavelength range of 570-630 nm). |
Targets
PLAUR
PLAUR Target Infomation Overview
- Target Symbol: PLAUR, plasminogen activator, urokinase receptor
- Gene Groups: CD molecules; LY6/PLAUR domain containing
- Alias: URKR; UPAR; CD87
- Alias Names: urokinase-type plasminogen activator (uPA) receptor; urokinase plasminogen activator surface receptor
PLAUR, plasminogen activator, urokinase receptor Target Infomation by Species
HumanMouseRat
Human PLAUR Target Information
- Target Symbol: PLAUR, plasminogen activator, urokinase receptor
- Alias:
- CD87
- monocyte activation antigen Mo3
- U-PAR
- u-plasminogen activator receptor form 2
- UPAR
- URKR
- urokinase plasminogen activator surface receptor
- urokinase-type plasminogen activator (uPA) receptor
- NCBI_Gene: 5329
- UniProtKB: Q03405
Human PLAUR Predicted Functions
Enables enzyme binding activity; protein domain specific binding activity; and signaling receptor binding activity. Involved in several processes, including negative regulation of apoptotic signaling pathway; positive regulation of epidermal growth factor receptor signaling pathway; and positive regulation of release of cytochrome c from mitochondria. Located in cell surface and plasma membrane. Implicated in rheumatoid arthritis. Biomarker of several diseases, including Lyme disease; cardiovascular system disease (multiple); end stage renal disease; hepatitis B; and melioidosis.
Mouse Plaur Target Information
- Target Symbol: Plaur, plasminogen activator, urokinase receptor
- Alias:
- Cd87
- u-PAR
- uPAR
- urokinase-type plasminogen activator receptor
- NCBI_Gene: 18793
Mouse Plaur Predicted Functions
Predicted to enable enzyme binding activity; protein domain specific binding activity; and signaling receptor binding activity. Predicted to be involved in several processes, including negative regulation of apoptotic signaling pathway; positive regulation of epidermal growth factor receptor signaling pathway; and positive regulation of release of cytochrome c from mitochondria. Is integral component of plasma membrane. Is expressed in several structures, including decidua; early conceptus; and spleen. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human PLAUR (plasminogen activator, urokinase receptor).
Rat Plaur Target Information
- Target Symbol: Plaur, plasminogen activator, urokinase receptor
- Alias:
- Par
- plasminogen activator urokinase receptor 3
- plasminogen activator, urokinase receptor 3
- Plaur3
- U-PAR
- uPAR
- uPAR-2
- uPAR-3
- urinary plasminogen activator receptor 2
- urinary plasminogen activator receptor 3
- urokinase plasminogen activator receptor
- urokinase plasminogen activator surface receptor
- NCBI_Gene: 50692
Rat Plaur Predicted Functions
Predicted to enable enzyme binding activity; protein domain specific binding activity; and signaling receptor binding activity. Involved in several processes, including epithelial cell differentiation involved in prostate gland development; skeletal muscle tissue regeneration; and spermatogenesis. Predicted to be located in cell surface. Predicted to be integral component of plasma membrane. Predicted to be active in plasma membrane. Biomarker of chronic obstructive pulmonary disease; myocardial infarction; and status epilepticus. Human ortholog(s) of this gene implicated in rheumatoid arthritis. Orthologous to human PLAUR (plasminogen activator, urokinase receptor).
