Mouse IL-23 ELISA Kit

$350.00$450.00

TARGETS IL23A
SPECIES Mouse
Sample Type Serum, plasma, cell culture supernatant, and other biological samples
Sample Volume 20 μL
Sensitivity 0.31 pg/mL
Range 1.56 pg/mL – 100 pg/mL
Assay Time 3.5 h
Recovery 80% – 99%
Average Recovery 0.91
Sample Type Serum, plasma, cell culture supernatant, and other biological samples
Sample Volume 20 μL
Sensitivity 0.31 pg/mL
Range 1.56 pg/mL – 100 pg/mL
Assay Time 3.5 h
Recovery 80% – 99%
Average Recovery 0.91
Intra Precision 3.0% – 5.4%
Inter-Precision 4.4% – 6.4%
Platform ELISA
Plate Detachable 96-well plate
Size 96T/48T
Storage If the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard solution should be stored at -20℃, while the other components should be stored at 4℃.
Delivery 4℃ blue ice transportation
Components 96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-IL-23 monoclonal antibody
Mouse IL-23 freeze-dried standard
IL-23 detect Antibody
Standard Diluent
Assay Buffer(10×)
Substrate TMB
Stop Solution
Washing Buffer(20×)
Sealing Film
Assay Principle This kit utilizes the double antibody sandwich enzyme-linked immunosorbent assay (ELISA) detection technique.Specific anti-mouse IL-23 antibodies are precoated on a high-affinity ELISA plate. Standard samples, test samples, and biotinylated detection antibodies are added to the wells of the ELISA plate. After incubation, IL-23 present in the samples binds to the solid-phase antibodies and the detection antibodies. After washing to remove unbound substances, streptavidin-HRP labeled with horseradish peroxidase is added. After washing, a colorimetric substrate, TMB, is added and the plate is incubated in the dark for color development. The intensity of the color reaction is directly proportional to the concentration of IL-23 in the samples.A stop solution is added to terminate the reaction, and the absorbance value is measured at a wavelength of 450 nm (with a reference wavelength range of 570-630 nm).

 

Targets

IL23A

IL23A Target Infomation Overview

  • Target Symbol: IL23A, interleukin 23 subunit alpha
  • Gene Groups: Interleukins
  • Alias: SGRF; IL23P19; IL-23; IL-23A; P19
  • Alias Names: interleukin-six, G-CSF related factor; interleukin 23, alpha subunit p19

IL23A, interleukin 23 subunit alpha Target Infomation by Species

[su_tabs][su_tab title=”Human” disabled=”no” anchor=”” url=”” target=”blank” class=”tab-human”]

Human IL23A Target Information

  • Target Symbol: IL23A, interleukin 23 subunit alpha
  • Alias:
    • IL-23
    • IL-23 subunit alpha
    • IL-23-A
    • IL-23A
    • IL-23p19
    • IL23P19
    • interleukin 23 p19 subunit
    • interleukin 23, alpha subunit p19
    • interleukin-23 subunit alpha
    • interleukin-23 subunit p19
    • interleukin-six, G-CSF related factor
    • JKA3 induced upon T-cell activation
    • MGC79388
    • P19
    • SGRF
  • NCBI_Gene: 51561
  • UniProtKB: Q9NPF7

Human IL23A Predicted Functions

Contributes to interleukin-23 receptor binding activity. Involved in several processes, including positive regulation of cytokine production; positive regulation of lymphocyte proliferation; and positive regulation of peptidyl-tyrosine phosphorylation. Part of interleukin-23 complex.

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[su_tab title=”Mouse” disabled=”no” anchor=”” url=”” target=”blank” class=”tab-mouse”]

Mouse Il23a Target Information

Mouse Il23a Predicted Functions

Contributes to interleukin-23 receptor binding activity. Involved in positive regulation of defense response to virus by host; positive regulation of immune response; and positive regulation of neutrophil chemotaxis. Acts upstream of or within T cell proliferation and positive regulation of transcription by RNA polymerase II. Located in extracellular space. Part of interleukin-23 complex. Is expressed in decidua; decidua basalis; embryo; and extraembryonic component. Orthologous to human IL23A (interleukin 23 subunit alpha).

[/su_tab]
[su_tab title=”Rat” disabled=”no” anchor=”” url=”” target=”blank” class=”tab-rat”]

Rat Il23a Target Information

  • Target Symbol: Il23a, interleukin 23 subunit alpha
  • Alias:
    • IL-23 subunit alpha
    • IL-23-A
    • IL-23p19
    • Interleukin 23, alpha subunit p19
    • interleukin-23 subunit alpha
    • interleukin-23 subunit p19
    • MGC114275
  • NCBI_Gene: 155140
  • UniProtKB: Q91Z84

Rat Il23a Predicted Functions

Predicted to enable cytokine activity. Predicted to contribute to interleukin-23 receptor binding activity. Predicted to be involved in several processes, including positive regulation of cytokine production; positive regulation of lymphocyte activation; and positive regulation of peptidyl-tyrosine phosphorylation. Predicted to act upstream of or within T cell proliferation and positive regulation of transcription by RNA polymerase II. Predicted to be located in extracellular space. Predicted to be part of interleukin-23 complex. Orthologous to human IL23A (interleukin 23 subunit alpha).

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IL23A Target News

[catlist tags=”il23a” template=targetnews thumbnail=yes thumbnail_class=”related-post-media clr” thumbnail_size=833]

4.3
Celastrol alleviates atopic dermatitis by regulating Ezrin-mediated mitochondrial fission and fusion
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
1.9
Thymic Stromal Lymphopoietin Activates Mouse Dendritic Cells Through the JAK/SYK Pathway in Promoting Th17 Response in Psoriasis
Balkan Medical Journal
4.9
GLP-1 receptor agonists alleviate colonic inflammation by modulating intestinal microbiota and the function of group 3 innate lymphoid cells
IMMUNOLOGY
4.8
Accurate network pharmacology and novel ingredients formula of herbal targeting estrogen signaling for psoriasis intervention
JOURNAL OF ETHNOPHARMACOLOGY
13.9
Photothermal Microneedle Hydrogel Patch for Refractory Soft Tissue Injuries through Thermosensitized Anti-Inflammaging Modulation
Small Structures
3.8
SGLT2 knockdown restores the Th17/Treg balance and suppresses diabetic nephropathy in db/db mice by regulating SGK1 via Na+
MOLECULAR AND CELLULAR ENDOCRINOLOGY
3.8
MiR-326 sponges TET2 triggering imbalance of Th17/Treg differentiation to exacerbate pyroptosis of hepatocytes in concanavalin A-induced autoimmune hepatitis
Annals of Hepatology
15.1
Transcutaneous Immunotherapy for RNAi: A Cascade-Responsive Decomposable Nanocomplex Based on Polyphenol-Mediated Framework Nucleic Acid in Psoriasis
Advanced Science
Cardiovascular Disease (Hypertension & Atherosclerosis & Acute Myocardial Infarction & Coronary Heart Disease)
Lung Disease (Asthma & COPD)
Multiple Sclerosis
Osteoarthrosis & Rheumatoid Arthritis
Systemic Lupus Erythematosus

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