HGNC ID: 1685
Target Abstract:
CD5 is a 67 kDa glycoprotein composed of a 347 amino acid extracellular domain and a 93 amino acid intracellular domain. It belongs to the scavenger receptor cysteine-rich (SRCR) family and is expressed in mature T cells and a small subset of normal B cells. CD5-positive T lymphocytes have signaling functions, while CD5-positive B lymphocytes not only have immune functions but are also closely associated with disease development.
CD5 Target Infomation Overview
- Target Symbol: CD5, CD5 molecule
- Gene Groups: CD molecules; Scavenger receptor cysteine rich domain containing
- Alias: T1
- Previous Names: LEU1
- Alias Names: CD5 antigen (p56-62)
CD5, CD5 molecule Target Infomation by Species
- Human
- Mouse
- Rat
Human CD5 Target Information
- Target Symbol: CD5, CD5 molecule
- Alias:
- cd5 antigen
- CD5 antigen (p56-62)
- LEU1
- lymphocyte antigen T1/Leu-1
- T-cell surface glycoprotein CD5
- T1
- NCBI_Gene: 921
- UniProtKB: P06127
Human CD5 Predicted Functions
Predicted to enable scavenger receptor activity. Predicted to be involved in T cell costimulation. Predicted to act upstream of or within apoptotic signaling pathway. Located in plasma membrane.
Mouse Cd5 Target Information
- Target Symbol: Cd5, CD5 antigen
- Alias:
- Ly-1
- Ly-12
- Ly-A
- lymphocyte antigen 1
- lymphocyte antigen 12
- Lyt-1
- T-lymphocyte antigen 1
- NCBI_Gene: 12507
Mouse Cd5 Predicted Functions
Predicted to enable scavenger receptor activity. Acts upstream of or within T cell costimulation and apoptotic signaling pathway. Located in external side of plasma membrane. Is expressed in gut and male reproductive gland or organ. Orthologous to human CD5 (CD5 molecule).
Rat Cd5 Target Information
- Target Symbol: Cd5, Cd5 molecule
- Alias:
- CD5 antigen
- LOC100911215
- lymphocyte antigen CD5
- MGC114334
- T-cell surface glycoprotein CD5
- T-cell surface glycoprotein CD5-like
- NCBI_Gene: 54236
Rat Cd5 Predicted Functions
Predicted to enable scavenger receptor activity. Predicted to be involved in T cell costimulation. Predicted to act upstream of or within apoptotic signaling pathway. Is spanning component of plasma membrane. Orthologous to human CD5 (CD5 molecule).