HGNC ID: 3685
FGF7 Target Infomation Overview
- Target Symbol: FGF7, fibroblast growth factor 7
- Gene Groups: Receptor ligands; Fibroblast growth factor family
- Alias: KGF
- Alias Names: keratinocyte growth factor; fibroblast growth factor 7 (keratinocyte growth factor)
FGF7, fibroblast growth factor 7 Target Infomation by Species
- Human
- Mouse
- Rat
Human FGF7 Target Information
- Target Symbol: FGF7, fibroblast growth factor 7
- Alias:
- FGF-7
- HBGF-7
- heparin-binding growth factor 7
- keratinocyte growth factor
- KGF
- NCBI_Gene: 2252
- UniProtKB: P21781
Human FGF7 Predicted Functions
Enables chemoattractant activity. Involved in several processes, including positive regulation of keratinocyte migration; positive regulation of keratinocyte proliferation; and protein localization to cell surface. Acts upstream of or within fibroblast growth factor receptor signaling pathway and positive regulation of epithelial cell proliferation involved in lung morphogenesis. Predicted to be located in extracellular region. Predicted to be active in cytoplasm and extracellular space. Biomarker of several diseases, including inflammatory bowel disease (multiple); leiomyoma; prostatic hypertrophy; reproductive organ cancer (multiple); and severe acute respiratory syndrome.
Mouse Fgf7 Target Information
- Target Symbol: Fgf7, fibroblast growth factor 7
- Alias:
- Keratinocyte growth factor
- Kgf
- NCBI_Gene: 14178
Mouse Fgf7 Predicted Functions
Predicted to enable heparin binding activity; receptor ligand activity; and type 2 fibroblast growth factor receptor binding activity. Involved in positive regulation of transcription, DNA-templated. Acts upstream of or within morphogenesis of an epithelium; positive regulation of epithelial cell proliferation; and regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling. Located in Golgi apparatus and extracellular region. Is expressed in several structures, including alimentary system; brain; embryo mesenchyme; genitourinary system; and integumental system. Orthologous to human FGF7 (fibroblast growth factor 7).
Rat Fgf7 Target Information
- Target Symbol: Fgf7, fibroblast growth factor 7
- Alias:
- FGF-7
- Fgf5b
- fibroblast growth factor 5b
- HBGF-7
- heparin-binding growth factor 7
- keratinocyte growth factor
- Keratinocyte Growth Factor Fgf-7
- Kgf
- KGF/FGF7
- NCBI_Gene: 29348
Rat Fgf7 Predicted Functions
Enables growth factor activity; heparin binding activity; and type 2 fibroblast growth factor receptor binding activity. Involved in several processes, including ovarian follicle development; phosphatidylcholine biosynthetic process; and surfactant homeostasis. Located in extracellular space. Orthologous to human FGF7 (fibroblast growth factor 7).
