C-reactive protein (CRP) is a cyclic, pentameric protein found in plasma. The liver can synthesize CRP in response to factors released by macrophages and adipocytes. CRP is a liver derived acute protein that increases after macrophages and T cells secrete interleukin-6. Its physiological function is to bind to lysophosphatidylcholine on the surface of dead or dying cells (and certain types of bacteria) to activate the complement system through C1Q complexes. It is not related to C-peptide (insulin) or protein C (coagulation). CRP is usually used as an inflammatory marker, and its level increases when the body is infected with inflammation. Recent studies have shown that patients with a higher basic level of CRP are usually accompanied by a higher incidence of diabetes, hypertension and cardiovascular disease