HGNC ID: 17655
GREM2 Target Infomation Overview
- Target Symbol: GREM2, gremlin 2, DAN family BMP antagonist
- Gene Groups: DAN family
- Alias: Prdc; FLJ21195; CKTSF1B2; DAND3
- Alias Names: protein related to DAN and cerberus; gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis); gremlin 2
GREM2, gremlin 2, DAN family BMP antagonist Target Infomation by Species
- Human
- Mouse
- Rat
Human GREM2 Target Information
- Target Symbol: GREM2, gremlin 2, DAN family BMP antagonist
- Alias:
- CKTSF1B2
- cysteine knot superfamily 1, BMP antagonist 2
- DAN domain family member 3
- DAND3
- gremlin 2 homolog, cysteine knot superfamily (xenopus laevis)
- gremlin 2, cysteine knot superfamily, homolog
- gremlin-2
- PRDC
- protein related to DAN and cerberus
- STHAG9
- NCBI_Gene: 64388
- UniProtKB: Q9H772
Human GREM2 Predicted Functions
Predicted to enable several functions, including BMP binding activity; heparin binding activity; and identical protein binding activity. Predicted to be involved in several processes, including determination of dorsal identity; embryonic body morphogenesis; and regulation of signal transduction. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Implicated in tooth agenesis.
Mouse Grem2 Target Information
- Target Symbol: Grem2, gremlin 2, DAN family BMP antagonist
- Alias:
- gremlin 2
- Prdc
- protein related to DAN and cerberus
- NCBI_Gene: 23893
Mouse Grem2 Predicted Functions
Enables BMP binding activity; heparin binding activity; and identical protein binding activity. Involved in several processes, including determination of dorsal identity; embryonic body morphogenesis; and regulation of signal transduction. Located in extracellular space. Is expressed in several structures, including chondrocranium; integument; intestine smooth muscle circular layer; lung; and neural tube. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human GREM2 (gremlin 2, DAN family BMP antagonist).
Rat Grem2 Target Information
- Target Symbol: Grem2, gremlin 2, DAN family BMP antagonist
- Alias:
- gremlin 2
- gremlin 2 homolog, cysteine knot superfamily
- gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
- gremlin 2, cysteine knot superfamily, homolog
- gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)
- gremlin-2
- LOC289264
- RGD1560008
- similar to PRDC
- NCBI_Gene: 289264
- UniProtKB: D3ZXD0
Rat Grem2 Predicted Functions
Predicted to enable several functions, including BMP binding activity; heparin binding activity; and identical protein binding activity. Predicted to be involved in several processes, including determination of dorsal identity; embryonic body morphogenesis; and regulation of signal transduction. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in tooth agenesis. Orthologous to human GREM2 (gremlin 2, DAN family BMP antagonist).