Follistatin, also known as activin binding protein, is encoded by the FST gene in humans. Follicle suppressin is an autocrine glycoprotein that is expressed in almost all tissues of higher animals. Follicle statin is produced by follicular astrocytes (FS) in the anterior pituitary gland. Its basic function is to bind and biologically neutralize TGF- β A member of a superfamily. People are currently studying the role of follicle hormones as antagonists of muscle growth inhibitors in regulating muscle growth in mice. Animal model experiments with spinal muscular atrophy have shown that increasing the levels of follicle suppressin in certain core muscle groups can increase life expectancy. In addition, people are also studying the relationship between follicle suppressin and polycystic ovary syndrome.