HGNC ID: 6373
Target Abstract:
CD161, also known as NKR-P1, CD161a/CD161b, NKP-P1a/KLRB1a, belongs to the C-type lectin superfamily. It is normally expressed in most NK cells (mature and immature, pre-NK), a small proportion of T cells and a small proportion of thymocytes. Abnormally expressed in aggressive and nasal NK cell leukemia/lymphoma, but not in primitive NK cell leukemia, lymphoma.
KLRB1 Target Infomation Overview
- Target Symbol: KLRB1, killer cell lectin like receptor B1
- Gene Groups: CD molecules; Killer cell lectin like receptors; C-type lectin domain containing
- Alias: CD161; NKR-P1; NKR-P1A; hNKR-P1A; CLEC5B
- Previous Names: NKR
- Alias Names: natural killer cell surface protein P1A; killer cell lectin-like receptor subfamily B, member 1
KLRB1, killer cell lectin like receptor B1 Target Infomation by Species
- Human
- Mouse
- Rat
Human KLRB1 Target Information
- Target Symbol: KLRB1, killer cell lectin like receptor B1
- Alias:
- C-type lectin domain family 5 member B
- CD161
- CLEC5B
- hNKR-P1A
- killer cell lectin-like receptor subfamily B member 1
- killer cell lectin-like receptor subfamily B, member 1
- MGC138614
- natural killer cell surface protein P1A
- NKR
- NKR-P1
- NKR-P1A
- NKRP1A
- NCBI_Gene: 3820
- UniProtKB: Q12918
Human KLRB1 Predicted Functions
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway. Predicted to be located in plasma membrane.
Mouse Klrb1a Target Information
- Target Symbol: Klrb1a, killer cell lectin-like receptor subfamily B member 1A
- Alias:
- Ly55a
- lymphocyte antigen 55 complex, locus A
- NKR-P1A
- Nkrp1-a
- NCBI_Gene: 17057
Mouse Klrb1a Predicted Functions
Predicted to enable carbohydrate binding activity. Located in plasma membrane. Orthologous to human KLRB1 (killer cell lectin like receptor B1).
Rat Klrb1a Target Information
- Target Symbol: Klrb1a, killer cell lectin-like receptor subfamily B, member 1A
- Alias:
- antigen 3.2.3
- CD161 antigen-like family member A
- killer cell lectin-like receptor subfamily B member 1A
- killer cell lectin-like receptor subfamily B, member 1A (mapped)
- Klrb1a_mapped
- natural killer cell surface protein P1-3.2.3
- NKR-P1 3.2.3
- NKR-P1A
- Nkrp1a
- NCBI_Gene: 362443
Rat Klrb1a Predicted Functions
Predicted to enable carbohydrate binding activity. Predicted to be located in plasma membrane. Orthologous to human KLRB1 (killer cell lectin like receptor B1).