Decorin is a secreted proteoglycan rich in the leucine low molecular weight proteoglycan (SLRP) family. Decorin regulates the biological activity of extracellular collagen matrix and matrix related growth factors FGF, GDF-8/Myostatin, TGF-beta, and WISP-1. It also binds and activates EGF receptors, ErbB4, and IGF-1 receptors. Decorin promotes myoblast differentiation, supports angiogenesis, and inhibits tumor development. Research has shown that Decorin may have an inhibitory effect on the contraction of hypertrophic scars, indicating a certain role in preventing hypertrophic scar formation and promoting scar maturation.