BID

HGNC ID: 1050

BID Target Infomation Overview

  • Target Symbol: BID, BH3 interacting domain death agonist
  • Gene Groups: Receptor ligands; BCL2 homology region 3 (BH3) only; MicroRNA protein coding host genes

BID, BH3 interacting domain death agonist Target Infomation by Species

  • human iconHuman
  • mouse iconMouse
  • rat iconRat

Human BID Target Information

  • Target Symbol: BID, BH3 interacting domain death agonist
  • Alias Names:
    • apoptic death agonist
    • BH3 interacting domain death agonist Si6 isoform
    • BH3-interacting domain death agonist
    • BID isoform ES(1b)
    • BID isoform L(2)
    • BID isoform Si6
    • desmocollin type 4
    • FP497
    • Human BID coding sequence
    • MGC15319
    • MGC42355
    • p22 BID
  • NCBI_Gene: NCBI_Gene: 637
  • UniProtKB: UniProtKB: P55957

Human BID Predicted Functions

Predicted to enable death receptor binding activity. Involved in several processes, including hepatocyte apoptotic process; positive regulation of apoptotic signaling pathway; and positive regulation of cellular component organization. Located in cytosol and mitochondrial outer membrane. Implicated in pancreatic cancer.

Mouse Bid Target Information

  • Target Symbol: Bid, BH3 interacting domain death agonist
  • Alias Names:
    • 2700049M22Rik
    • AI875481
    • AU022477
    • expressed sequence AI875481
    • expressed sequence AU022477
    • RIKEN cDNA 2700049M22 gene
  • NCBI_Gene: NCBI_Gene: 12122
  • UniProtKB:

Mouse Bid Predicted Functions

Enables ubiquitin protein ligase binding activity. Involved in positive regulation of cellular component organization; protein-containing complex assembly; and release of cytochrome c from mitochondria. Acts upstream of or within several processes, including apoptotic signaling pathway; hepatocyte apoptotic process; and regulation of apoptotic process. Located in cytosol; membrane; and mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human BID (BH3 interacting domain death agonist).

Rat Bid Target Information

  • Target Symbol: Bid, BH3 interacting domain death agonist
  • Alias Names:
    • apoptotic death agonist BID
    • BH3-interacting domain death agonist
    • desmocollin type 4
    • p22 BID
  • NCBI_Gene: NCBI_Gene: 64625
  • UniProtKB:

Rat Bid Predicted Functions

Predicted to enable ubiquitin protein ligase binding activity. Involved in several processes, including positive regulation of autophagy in response to ER overload; release of cytochrome c from mitochondria; and response to ischemia. Located in cytosol and mitochondrion. Used to study pre-malignant neoplasm. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human BID (BH3 interacting domain death agonist).