HGNC ID: 1050
BID Target Infomation Overview
- Target Symbol: BID, BH3 interacting domain death agonist
- Gene Groups: Receptor ligands; BCL2 homology region 3 (BH3) only; MicroRNA protein coding host genes
BID, BH3 interacting domain death agonist Target Infomation by Species
- Human
- Mouse
- Rat
Human BID Target Information
- Target Symbol: BID, BH3 interacting domain death agonist
- Alias Names:
- apoptic death agonist
- BH3 interacting domain death agonist Si6 isoform
- BH3-interacting domain death agonist
- BID isoform ES(1b)
- BID isoform L(2)
- BID isoform Si6
- desmocollin type 4
- FP497
- Human BID coding sequence
- MGC15319
- MGC42355
- p22 BID
- NCBI_Gene: NCBI_Gene: 637
- UniProtKB: UniProtKB: P55957
Human BID Predicted Functions
Predicted to enable death receptor binding activity. Involved in several processes, including hepatocyte apoptotic process; positive regulation of apoptotic signaling pathway; and positive regulation of cellular component organization. Located in cytosol and mitochondrial outer membrane. Implicated in pancreatic cancer.
Mouse Bid Target Information
- Target Symbol: Bid, BH3 interacting domain death agonist
- Alias Names:
- 2700049M22Rik
- AI875481
- AU022477
- expressed sequence AI875481
- expressed sequence AU022477
- RIKEN cDNA 2700049M22 gene
- NCBI_Gene: NCBI_Gene: 12122
- UniProtKB:
Mouse Bid Predicted Functions
Enables ubiquitin protein ligase binding activity. Involved in positive regulation of cellular component organization; protein-containing complex assembly; and release of cytochrome c from mitochondria. Acts upstream of or within several processes, including apoptotic signaling pathway; hepatocyte apoptotic process; and regulation of apoptotic process. Located in cytosol; membrane; and mitochondrion. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human BID (BH3 interacting domain death agonist).
Rat Bid Target Information
- Target Symbol: Bid, BH3 interacting domain death agonist
- Alias Names:
- apoptotic death agonist BID
- BH3-interacting domain death agonist
- desmocollin type 4
- p22 BID
- NCBI_Gene: NCBI_Gene: 64625
- UniProtKB:
Rat Bid Predicted Functions
Predicted to enable ubiquitin protein ligase binding activity. Involved in several processes, including positive regulation of autophagy in response to ER overload; release of cytochrome c from mitochondria; and response to ischemia. Located in cytosol and mitochondrion. Used to study pre-malignant neoplasm. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human BID (BH3 interacting domain death agonist).
