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Human BMP-6 ELISA Kit
$350.00 – $450.00
| Sample Type | Serum, plasma, cell culture supernatant, and other biological samples |
|---|---|
| Sample Volume | 20 μL |
| Sensitivity | 1.01 pg/mL |
| Range | 62.5 pg/mL – 4000 pg/mL |
| Assay Time | 3.5 h |
| Recovery | 87% – 100% |
| Average Recovery | 0.9 |
| Intra Precision | 2.0% – 4.1% |
| Inter-Precision | 1.9% – 4.9% |
| Platform | ELISA |
| Plate | Detachable 96-well plate |
| Size | 96T/48T |
| Storage | If the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard solution should be stored at -20℃, while the other components should be stored at 4℃. |
| Delivery | 4℃ blue ice transportation |
| Components | 96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-BMP-6 monoclonal antibody Human BMP-6 freeze-dried standard BMP-6 detect Antibody Standard Diluent Assay Buffer(10×) Substrate TMB Stop Solution Washing Buffer(20×) Sealing Film |
| Assay Principle | This kit utilizes the double antibody sandwich enzyme-linked immunosorbent assay (ELISA) detection technique.Specific anti-human BMP-6 antibodies are precoated on a high-affinity ELISA plate.Standards and test samples are added to the wells of the ELISA plate. After incubation, the BMP-6 present in the samples binds to the solid-phase antibodies. After washing to remove unbound substances, biotinylated detection antibodies are added and incubated. After washing to remove unbound biotinylated antibodies, streptavidin-HRP labeled with horseradish peroxidase is added. After washing, a colorimetric substrate, TMB, is added and the plate is incubated in the dark for color development. The intensity of the color reaction is directly proportional to the concentration of BMP-6 in the samples.A stop solution is added to terminate the reaction, and the absorbance value is measured at a wavelength of 450 nm (with a reference wavelength range of 570-630 nm). |
Targets
BMP6
BMP6 Target Infomation Overview
- Target Symbol: BMP6, bone morphogenetic protein 6
- Gene Groups: Bone morphogenetic proteins
- Alias: VGR1
- Previous Names: VGR
- Alias Names: vegetal related growth factor (TGFB-related)
BMP6, bone morphogenetic protein 6 Target Infomation by Species
HumanMouseRat
Human BMP6 Target Information
- Target Symbol: BMP6, bone morphogenetic protein 6
- Alias:
- BMP-6
- vegetal related growth factor (TGFB-related)
- vegetal-related (TGFB related) cytokine
- VG-1-R
- VG-1-related protein
- Vg1-related sequence
- VGR
- VGR-1
- VGR1
- NCBI_Gene: 654
- UniProtKB: P22004
Human BMP6 Predicted Functions
Enables BMP receptor binding activity and protein heterodimerization activity. Involved in several processes, including negative regulation of adherens junction organization; positive regulation of macromolecule metabolic process; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to be located in cytoplasm and vesicle. Predicted to be active in extracellular space. Biomarker of breast cancer; esophagus squamous cell carcinoma; prostate cancer; and renal cell carcinoma.
Mouse Bmp6 Target Information
- Target Symbol: Bmp6, bone morphogenetic protein 6
- Alias:
- D13Wsu115e
- DNA segment, Chr 13, Wayne State University 115, expressed
- Vg-1 related protein 1
- Vgr1
- NCBI_Gene: 12161
Mouse Bmp6 Predicted Functions
Predicted to enable BMP receptor binding activity; protein heterodimerization activity; and receptor ligand activity. Involved in several processes, including iron ion homeostasis; positive regulation of signal transduction; and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including endochondral ossification; male genitalia development; and osteoblast differentiation. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; female reproductive system; sensory organ; and skeleton. Orthologous to human BMP6 (bone morphogenetic protein 6).
Rat Bmp6 Target Information
- Target Symbol: Bmp6, bone morphogenetic protein 6
- Alias:
- BMP-6
- VG-1-related protein
- VGR
- VGR-1
- NCBI_Gene: 25644
- UniProtKB: Q04906
Rat Bmp6 Predicted Functions
Enables growth factor activity. Involved in several processes, including cellular response to mechanical stimulus; positive regulation of aldosterone secretion; and positive regulation of cell differentiation. Located in cytoplasm; extracellular space; and vesicle. Biomarker of anemia; brain ischemia; and colitis. Orthologous to human BMP6 (bone morphogenetic protein 6).
