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Human LDL Receptor/LDLR ELISA Kit
$350.00 – $450.00
| Sample Type | Serum, plasma, cell culture supernatant, and other biological samples |
|---|---|
| Sample Volume | 10 μL |
| Sensitivity | 6.32 pg/mL |
| Range | 125.00 pg/mL – 8000 pg/mL |
| Assay Time | 3.5 h |
| Recovery | 101%112% |
| Average Recovery | 1.07 |
| Intra Precision | 3.0% – 4.3% |
| Inter-Precision | 2.3% – 3.6% |
| Platform | ELISA |
| Plate | Detachable 96-well plate |
| Size | 96T/48T |
| Storage | If the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard solution should be stored at -20℃, while the other components should be stored at 4℃. |
| Delivery | 4℃ blue ice transportation |
| Components | 96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-LDLR monoclonal antibody Human LDLR freeze-dried standard LDLR detect Antibody Assay Buffer(10×) Substrate TMB Stop Solution Washing Buffer(20×) Sealing Film |
| Assay Principle | This kit utilizes the double antibody sandwich enzyme-linked immunosorbent assay (ELISA) detection technique.Specific anti-human LDLR antibodies are precoated on a high-affinity ELISA plate. Standard samples, test samples, and the detection antibody labeled with horseradish peroxidase are added to the wells of the ELISA plate. After incubation, LDLR present in the samples binds to the solid-phase antibodies and the detection antibodies. After washing, a colorimetric substrate, TMB, is added and the plate is incubated in the dark for color development. The intensity of the color reaction is directly proportional to the concentration of LDLR in the samples. A stop solution is added to terminate the reaction, and the absorbance value is measured at a wavelength of 450 nm (with a reference wavelength range of 570-630 nm). |
Targets
LDLR
LDLR Target Infomation Overview
- Target Symbol: LDLR, low density lipoprotein receptor
- Gene Groups: Low density lipoprotein receptors; MicroRNA protein coding host genes
- Alias: LDLCQ2
- Alias Names: familial hypercholesterolemia
LDLR, low density lipoprotein receptor Target Infomation by Species
HumanMouseRat
Human LDLR Target Information
- Target Symbol: LDLR, low density lipoprotein receptor
- Alias:
- FH
- FHC
- FHCL1
- LDL receptor
- LDLCQ2
- low-density lipoprotein receptor
- low-density lipoprotein receptor class A domain-containing protein 3
- NCBI_Gene: 3949
- UniProtKB: P01130
Human LDLR Predicted Functions
Enables several functions, including low-density lipoprotein particle binding activity; low-density lipoprotein particle receptor activity; and very-low-density lipoprotein particle receptor activity. Involved in several processes, including cholesterol homeostasis; cholesterol transport; and long-term memory. Located in several cellular components, including clathrin-coated pit; endosome; and external side of plasma membrane. Part of PCSK9-LDLR complex and receptor complex. Implicated in Alzheimer’s disease; arteriosclerosis; familial hypercholesterolemia; hepatitis C; and migraine without aura. Biomarker of systemic lupus erythematosus.
Mouse Ldlr Target Information
- Target Symbol: Ldlr, low density lipoprotein receptor
- Alias:
- 无
- NCBI_Gene: 16835
Mouse Ldlr Predicted Functions
Enables several functions, including amyloid-beta binding activity; low-density lipoprotein particle binding activity; and low-density lipoprotein particle receptor activity. Involved in several processes, including lipid transport; regulation of inflammatory response; and regulation of lipid metabolic process. Acts upstream of or within several processes, including cholesterol homeostasis; lipoprotein catabolic process; and low-density lipoprotein particle clearance. Located in several cellular components, including basolateral plasma membrane; endosome; and lysosome. Is expressed in several structures, including alimentary system; genitourinary system; musculoskeletal system; paravertebral ganglion; and sensory organ. Used to study familial hypercholesterolemia and fatty liver disease. Human ortholog(s) of this gene implicated in Alzheimer’s disease; arteriosclerosis; familial hypercholesterolemia; hepatitis C; and migraine without aura. Orthologous to human LDLR (low density lipoprotein receptor).
Rat Ldlr Target Information
- Target Symbol: Ldlr, low density lipoprotein receptor
- Alias:
- LDL receptor
- LDLRA
- low-density lipoprotein receptor
- NCBI_Gene: 300438
Rat Ldlr Predicted Functions
Enables low-density lipoprotein particle receptor activity. Involved in several processes, including cholesterol homeostasis; positive regulation of triglyceride catabolic process; and response to glucagon. Located in caveola and recycling endosome membrane. Used to study atherosclerosis and xanthomatosis. Human ortholog(s) of this gene implicated in Alzheimer’s disease; arteriosclerosis; familial hypercholesterolemia; hepatitis C; and migraine without aura. Orthologous to human LDLR (low density lipoprotein receptor).
