Name: EasyGo!™ Mouse IL6RA One-Step ELISA Kit
SKU: EK2153EG
Availability: InStock

EK2153EG

EasyGo!™ Mouse IL6RA One-Step ELISA Kit

$349.00 – $499.00

Related Target	IL6R
Species	mouse
Sample Type	Serum, plasma, cell culture supernatant, and other biological samples
Sample Volume	100uL(diluent)
Sensitivity	0.34 pg/ml
Array Range	6.25-400pg/ml
Assay Time	90min
Recovery	70%-130%
Average Recovery	/

SKU: EK2153EG Category: EasyGo! One-Step ELISA Kit

ELISA Kit Detail Information

Related Target	IL6R
Species	mouse
Sample Type	Serum, plasma, cell culture supernatant, and other biological samples
Sample Volume	100uL(diluent)
Sensitivity	0.34 pg/ml
Array Range	6.25-400pg/ml
Assay Time	90min
Recovery	70%-130%
Average Recovery	/
Intra Precision	< 10%
Inter Precision	< 10%
Plate	Detachable 96-well Plate
Storage	2-8℃
Delivery	blue ice
Components	Coated Microplate standard Assay Buffer (10×) TMB Stop Solution Washing Buffer (20×)
Assay Principle	This assay employs the quantitative sandwich enzyme immunoassay technique. A monoclonal antibody specific for Mouse IL-18 has been immobilized onto microwells, and one pellet of the HRP-linked detect antibody specific for IL-18 (light yellow) is pre-placed in the microwells, sealed by the adhesive film. Standard or samples are pipetted into the wells, then IL-18 present is bound by the immobilized antibody and detect antibody in the incubation. After washing, substrate solution reacts with HRP and color develops in proportion to the amount of IL-18 bound by the immobilized antibody. The color development is stopped and the intensity of the color is measured by microplate reader.

Related Targets

IL6R

IL6R Target Infomation Overview

Target Symbol: IL6R, interleukin 6 receptor
Gene Groups: CD molecules; Immunoglobulin like domain containing; Interleukin receptors
Alias: CD126; IL-6R; IL-1Ra; IL6RA; gp80
Alias Names: membrane glycoprotein 80; interleukin 6 receptor subunit alpha

IL6R, interleukin 6 receptor Target Infomation by Species

Human
Mouse
Rat

Human IL6R Target Information

Target Symbol: IL6R, interleukin 6 receptor
Alias:
- CD126
- CD126 antigen
- gp80
- HIES5
- IL-1Ra
- IL-6 receptor subunit alpha
- IL-6R
- IL-6R 1
- IL-6R subunit alpha
- IL-6R-1
- IL-6R-alpha
- IL-6RA
- IL6Q
- IL6QTL
- IL6RA
- IL6RQ
- interleukin 6 receptor alpha subunit
- interleukin-6 receptor subunit alpha
- membrane glycoprotein 80
- MGC104991
NCBI_Gene: 3570
UniProtKB: P08887

Human IL6R Predicted Functions

Enables cytokine binding activity; enzyme binding activity; and protein homodimerization activity. Contributes to ciliary neurotrophic factor receptor activity; interleukin-6 receptor activity; and interleukin-6 receptor binding activity. Involved in several processes, including cytokine-mediated signaling pathway; positive regulation of cell population proliferation; and positive regulation of macromolecule metabolic process. Located in apical plasma membrane and extracellular space. Part of ciliary neurotrophic factor receptor complex and interleukin-6 receptor complex. Implicated in Alzheimer’s disease; Huntington’s disease; hyper IgE syndrome; obesity; and stomach cancer. Biomarker of several diseases, including Graves’ disease; obesity; proliferative diabetic retinopathy; pulmonary tuberculosis; and sleep apnea.

Mouse Il6ra Target Information

Target Symbol: Il6ra, interleukin 6 receptor, alpha
Alias:
- CD126
- IL-6 receptor alpha chain
- IL-6R
- Il6r
- interleukin 6 receptor
NCBI_Gene: 16194

Mouse Il6ra Predicted Functions

Enables interleukin-6 binding activity and interleukin-6 receptor activity. Involved in T-helper 17 cell lineage commitment and interleukin-6-mediated signaling pathway. Located in cell surface. Part of interleukin-6 receptor complex. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system; and nervous system. Human ortholog(s) of this gene implicated in Alzheimer’s disease; Huntington’s disease; hyper IgE syndrome; obesity; and stomach cancer. Orthologous to human IL6R (interleukin 6 receptor).

Rat Il6r Target Information

Target Symbol: Il6r, interleukin 6 receptor
Alias:
- IL-6 receptor subunit alpha
- IL-6R 1
- IL-6R subunit alpha
- IL-6R-alpha
- IL-6RA
- IL6R1
- Il6ra
- interleukin 6 receptor, alpha
- interleukin-6 receptor subunit alpha
NCBI_Gene: 24499
- UniprotKB: G3V8T6
- UniprotKB: P22273

Rat Il6r Predicted Functions

Predicted to enable several functions, including cytokine binding activity; cytokine receptor activity; and protein homodimerization activity. Predicted to contribute to ciliary neurotrophic factor receptor activity and interleukin-6 receptor binding activity. Involved in several processes, including response to cAMP; response to gamma radiation; and response to lipopolysaccharide. Located in extracellular space and neuronal cell body membrane. Biomarker of several diseases, including congestive heart failure; mental depression; orchitis; sciatic neuropathy; and visual epilepsy. Human ortholog(s) of this gene implicated in Alzheimer’s disease; Huntington’s disease; hyper IgE syndrome; obesity; and stomach cancer. Orthologous to human IL6R (interleukin 6 receptor).

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