Human BMP-7 ELISA Kit

$350.00$450.00

TARGETS BMP7
SPECIES Human
Sample Type Serum, plasma, cell culture supernatant, and other biological samples
Sample Volume 20 μL
Sensitivity 2.06 pg/mL
Range 7.81 pg/mL – 500 pg/mL
Assay Time 3.5 h
Recovery 74% – 120%
Average Recovery 0.98
Sample Type Serum, plasma, cell culture supernatant, and other biological samples
Sample Volume 20 μL
Sensitivity 2.06 pg/mL
Range 7.81 pg/mL – 500 pg/mL
Assay Time 3.5 h
Recovery 74% – 120%
Average Recovery 0.98
Intra Precision 4.4% – 5.3%
Inter-Precision 2.2% – 4.9%
Platform ELISA
Plate Detachable 96-well plate
Size 96T/48T
Storage If the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard solution should be stored at -20℃, while the other components should be stored at 4℃.
Delivery 4℃ blue ice transportation
Components 96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-TRAIL/TNFSF10 monoclonal antibody
Human TRAIL/TNFSF10 freeze-dried standard
TRAIL/TNFSF10 detect Antibody
Standard Diluent
Assay Buffer(10×)
Substrate TMB
Stop Solution
Washing Buffer(20×)
Sealing Film
Assay Principle This kit utilizes the double antibody sandwich enzyme-linked immunosorbent assay (ELISA) detection technique.Specific anti-human BMP-7 antibodies are precoated on a high-affinity ELISA plate. Standard samples, test samples, and biotinylated detection antibodies are added to the wells of the ELISA plate. After incubation, BMP-7 present in the samples binds to the solid-phase antibodies and the detection antibodies. After washing to remove unbound substances, streptavidin-HRP labeled with horseradish peroxidase is added. After washing, a colorimetric substrate, TMB, is added and the plate is incubated in the dark for color development. The intensity of the color reaction is directly proportional to the concentration of BMP-7 in the samples.A stop solution is added to terminate the reaction, and the absorbance value is measured at a wavelength of 450 nm (with a reference wavelength range of 570-630 nm).

 

Targets

BMP7

BMP7 Target Infomation Overview

  • Target Symbol: BMP7, bone morphogenetic protein 7
  • Gene Groups: Bone morphogenetic proteins
  • Alias: OP-1
  • Alias Names: osteogenic protein 1

BMP7, bone morphogenetic protein 7 Target Infomation by Species

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Human BMP7 Target Information

Human BMP7 Predicted Functions

Predicted to enable BMP receptor binding activity and cytokine activity. Involved in several processes, including regulation of gene expression; regulation of protein phosphorylation; and transmembrane receptor protein serine/threonine kinase signaling pathway. Acts upstream of or within negative regulation of neuron differentiation and neuron projection morphogenesis. Located in extracellular space. Implicated in prostate cancer. Biomarker of breast cancer; ovarian carcinoma; prostate cancer; and renal cell carcinoma.

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Mouse Bmp7 Target Information

Mouse Bmp7 Predicted Functions

Predicted to enable BMP receptor binding activity; cytokine activity; and heparin binding activity. Involved in several processes, including allantois development; animal organ development; and chordate embryonic development. Acts upstream of or within several processes, including embryonic morphogenesis; morphogenesis of a branching epithelium; and regulation of morphogenesis of a branching structure. Located in extracellular space. Is expressed in several structures, including alimentary system; embryo ectoderm; embryo mesenchyme; genitourinary system; and sensory organ. Used to study obstructive sleep apnea and osteoarthritis. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human BMP7 (bone morphogenetic protein 7).

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Rat Bmp7 Target Information

Rat Bmp7 Predicted Functions

Enables heparin binding activity. Involved in several processes, including response to estradiol; response to peptide hormone; and response to vitamin D. Located in collagen-containing extracellular matrix; extracellular space; and vesicle. Biomarker of acute kidney tubular necrosis; kidney disease; nephroblastoma; and pyelonephritis. Human ortholog(s) of this gene implicated in prostate cancer. Orthologous to human BMP7 (bone morphogenetic protein 7).

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BMP7 Target News

[catlist tags=”bmp7″ template=targetnews thumbnail=yes thumbnail_class=”related-post-media clr” thumbnail_size=833]

Multiple Sclerosis
Osteoarthrosis & Rheumatoid Arthritis
Osteoporosis

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