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Human Granzyme A ELISA Kit
$350.00 – $450.00
| Sample Type | Serum, plasma, cell culture supernatant, and other biological samples |
|---|---|
| Sample Volume | 50 μL |
| Sensitivity | 0.31 pg/mL |
| Range | 15.63 pg/mL – 1000 pg/mL |
| Assay Time | 3.5 h |
| Recovery | 80% – 124% |
| Average Recovery | 1.12 |
| Intra Precision | 2.6% – 3.5% |
| Inter-Precision | 3.0% – 5.3% |
| Platform | ELISA |
| Plate | Detachable 96-well plate |
| Size | 96T/48T |
| Storage | If the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard solution should be stored at -20℃, while the other components should be stored at 4℃. |
| Delivery | 4℃ blue ice transportation |
| Components | 96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-Granzyme A monoclonal antibody Human Granzyme A freeze-dried standard Granzyme A detect Antibody Standard Diluent Assay Buffer(10×) Substrate TMB Stop Solution Washing Buffer(20×) Sealing Film |
| Assay Principle | This kit utilizes the double antibody sandwich enzyme-linked immunosorbent assay (ELISA) detection technique.Specific anti-human Granzyme A antibodies are precoated on a high-affinity ELISA plate. Standard samples, test samples, and biotinylated detection antibodies are added to the wells of the ELISA plate. After incubation, Granzyme A present in the samples binds to the solid-phase antibodies and the detection antibodies. After washing to remove unbound substances, streptavidin-HRP labeled with horseradish peroxidase is added. After washing, a colorimetric substrate, TMB, is added and the plate is incubated in the dark for color development. The intensity of the color reaction is directly proportional to the concentration of Granzyme A in the samples.A stop solution is added to terminate the reaction, and the absorbance value is measured at a wavelength of 450 nm (with a reference wavelength range of 570-630 nm). |
Targets
GZMA
GZMA Target Infomation Overview
- Target Symbol: GZMA, granzyme A
- Gene Groups: Granule associated serine proteases of immune defence
- Previous Names: HFSP; CTLA3
- Alias Names: CTL tryptase; Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); granzyme 1; granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
GZMA, granzyme A Target Infomation by Species
HumanMouseRat
Human GZMA Target Information
- Target Symbol: GZMA, granzyme A
- Alias:
- CTL tryptase
- CTLA3
- cytotoxic T-lymphocyte proteinase 1
- cytotoxic T-lymphocyte-associated serine esterase-3
- fragmentin-1
- granzyme 1
- Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3, Hanukah factor serine protease)
- granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
- granzyme-1
- h factor
- hanukah factor serine protease
- Hanukah factor serine protease)
- hanukkah factor
- HF
- HFSP
- NCBI_Gene: 3001
- UniProtKB: P12544
Human GZMA Predicted Functions
Enables protein homodimerization activity and serine-type endopeptidase activity. Involved in several processes, including cytotoxic T cell pyroptotic process; granzyme-mediated programmed cell death signaling pathway; and negative regulation of endodeoxyribonuclease activity. Predicted to be located in immunological synapse and nucleus. Biomarker of chronic obstructive pulmonary disease.
Mouse Gzma Target Information
- Target Symbol: Gzma, granzyme A
- Alias:
- AW494114
- BLT esterase
- Ctla-3
- Ctla3
- cytotoxic T lymphocyte-associated protein 3
- expressed sequence AW494114
- H factor
- Hanukah factor
- Hf
- SE1
- serine esterase 1
- TSP-1
- TSP1
- NCBI_Gene: 14938
Mouse Gzma Predicted Functions
Enables serine-type peptidase activity. Acts upstream of or within response to bacterium. Located in nucleus. Is expressed in thymus primordium. Orthologous to human GZMA (granzyme A).
Rat Gzma Target Information
- Target Symbol: Gzma, granzyme A
- Alias:
- 无
- NCBI_Gene: 266708
Rat Gzma Predicted Functions
Predicted to enable protein homodimerization activity and serine-type endopeptidase activity. Predicted to be involved in several processes, including cytotoxic T cell pyroptotic process; granzyme-mediated programmed cell death signaling pathway; and negative regulation of endodeoxyribonuclease activity. Predicted to act upstream of or within response to bacterium. Predicted to be located in nucleus. Orthologous to human GZMA (granzyme A).
GZMA Target News
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