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Human Tie1 ELISA Kit
$350.00 – $450.00
| Sample Type | Serum, plasma, cell culture supernatant, and other biological samples |
|---|---|
| Sample Volume | 20 μL |
| Sensitivity | 107.84 pg/mL |
| Range | 0.31 ng/mL – 20 ng/mL |
| Assay Time | 3.5 h |
| Recovery | 82% – 120% |
| Average Recovery | 0.94 |
| Intra Precision | 3.1%-4.0% |
| Inter-Precision | 1.2% – 3.7% |
| Platform | ELISA |
| Plate | Detachable 96-well plate |
| Size | 96T/48T |
| Storage | If the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard solution should be stored at -20℃, while the other components should be stored at 4℃. |
| Delivery | 4℃ blue ice transportation |
| Components | 96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-Tie1 monoclonal antibody Human Tie1 freeze-dried standard Tie1 detect Antibody Standard Diluent Assay Buffer(10×) Substrate TMB Stop Solution Washing Buffer(20×) Sealing Film |
| Assay Principle | This kit utilizes the double antibody sandwich enzyme-linked immunosorbent assay (ELISA) detection technique.Specific anti-human Tie1 antibodies are precoated on a high-affinity ELISA plate. Standard samples, test samples, and the detection antibody labeled with horseradish peroxidase are added to the wells of the ELISA plate. After incubation, Tie1 present in the samples binds to the solid-phase antibody and the detection antibody. After washing, a colorimetric substrate, TMB, is added and the plate is incubated in the dark for color development. The intensity of the color reaction is directly proportional to the concentration of Tie1 in the samples.A stop solution is added to terminate the reaction, and the absorbance value is measured at a wavelength of 450 nm (with a reference wavelength range of 570-630 nm). |
Targets
TIE1
TIE1 Target Infomation Overview
- Target Symbol: TIE1, tyrosine kinase with immunoglobulin like and EGF like domains 1
- Gene Groups: Receptor tyrosine kinases; Fibronectin type III domain containing; Immunoglobulin like domain containing
- Alias: JTK14
- Previous Names: TIE
- Alias Names: tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1; tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TIE1, tyrosine kinase with immunoglobulin like and EGF like domains 1 Target Infomation by Species
HumanMouseRat
Human TIE1 Target Information
- Target Symbol: TIE1, tyrosine kinase with immunoglobulin like and EGF like domains 1
- Alias:
- JTK14
- LMPHM11
- receptor tyrosine kinase
- soluble TIE1 variant 1
- soluble TIE1 variant 2
- soluble TIE1 variant 3
- soluble TIE1 variant 4
- soluble TIE1 variant 5
- TIE
- tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1
- tyrosine kinase with immunoglobulin-like and EGF-like domains 1
- tyrosine-protein kinase receptor Tie-1
- NCBI_Gene: 7075
- UniProtKB: P35590
Human TIE1 Predicted Functions
Predicted to enable transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in several processes, including circulatory system development; positive regulation of angiogenesis; and positive regulation of kinase activity. Predicted to act upstream of or within several processes, including negative regulation of angiogenesis; plasma membrane fusion; and vasculature development. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Implicated in hereditary lymphedema.
Mouse Tie1 Target Information
- Target Symbol: Tie1, tyrosine kinase with immunoglobulin-like and EGF-like domains 1
- Alias:
- D430008P04Rik
- RIKEN cDNA D430008P04 gene
- TIE
- tie-1
- NCBI_Gene: 21846
Mouse Tie1 Predicted Functions
Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in circulatory system development; response to retinoic acid; and tissue remodeling. Acts upstream of or within several processes, including negative regulation of angiogenesis; plasma membrane fusion; and vasculature development. Located in plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; extraembryonic component; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human TIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1).
Rat Tie1 Target Information
- Target Symbol: Tie1, tyrosine kinase with immunoglobulin-like and EGF-like domains 1
- Alias:
- tyrosine kinase receptor 1
- tyrosine-protein kinase receptor Tie-1
- NCBI_Gene: 89806
- UniProtKB: B5DFD6
Rat Tie1 Predicted Functions
Predicted to enable transmembrane receptor protein tyrosine kinase activity. Involved in vasculogenesis. Predicted to be located in plasma membrane. Predicted to be part of receptor complex. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human TIE1 (tyrosine kinase with immunoglobulin like and EGF like domains 1).
