EK168EG

EasyGo!™ Human CXCL10/IP-10 One-Step ELISA Kit

$349.00$499.00

 DATASHEET
Related Target
Specieshuman
Sample TypeSerum, plasma, cell culture supernatant, and other biological samples
Sample Volume50uL
Sensitivity1.33pg/ml
Array Range15.63-1000pg/ml
Assay Time90min
Recovery70%-130%
Average Recovery/
SKU: EK168EG Category:

ELISA Kit Detail Information

Related Target
Specieshuman
Sample TypeSerum, plasma, cell culture supernatant, and other biological samples
Sample Volume50uL
Sensitivity1.33pg/ml
Array Range15.63-1000pg/ml
Assay Time90min
Recovery70%-130%
Average Recovery/
Intra Precision< 10%
Inter Precision< 10%
PlateDetachable 96-well Plate
Storage2-8℃
Deliveryblue ice
ComponentsCoated Microplate
standard
Assay Buffer (10×)
TMB
Stop Solution
Washing Buffer (20×)
Assay PrincipleThis assay employs the quantitative sandwich enzyme immunoassay technique. A monoclonal antibody specific for Mouse IL-18 has been immobilized onto microwells, and one pellet of the HRP-linked detect antibody specific for IL-18 (light yellow) is pre-placed in the microwells, sealed by the adhesive film. Standard or samples are pipetted into the wells, then IL-18 present is bound by the immobilized antibody and detect antibody in the incubation. After washing, substrate solution reacts with HRP and color develops in proportion to the amount of IL-18 bound by the immobilized antibody. The color development is stopped and the intensity of the color is measured by microplate reader.

Related Targets

CXCL10

CXCL10 Target Infomation Overview

  • Target Symbol: CXCL10, C-X-C motif chemokine ligand 10
  • Gene Groups: Chemokine ligands
  • Alias: IFI10; IP-10; crg-2; mob-1; C7; gIP-10
  • Previous Names: INP10; SCYB10
  • Alias Names: small inducible cytokine subfamily B (Cys-X-Cys), member 10; chemokine (C-X-C motif) ligand 10

CXCL10, C-X-C motif chemokine ligand 10 Target Infomation by Species

  • Human
  • Mouse
  • Rat

Human CXCL10 Target Information

  • Target Symbol: CXCL10, C-X-C motif chemokine ligand 10
  • Alias:
    • 10 kDa interferon gamma-induced protein
    • C-X-C motif chemokine 10
    • C7
    • chemokine (C-X-C motif) ligand 10
    • crg-2
    • gamma IP10
    • gamma-IP10
    • gIP-10
    • IFI10
    • INP10
    • interferon-inducible cytokine IP-10
    • IP-10
    • mob-1
    • protein 10 from interferon (gamma)-induced cell line
    • SCYB10
    • small inducible cytokine subfamily B (Cys-X-Cys), member 10
    • small-inducible cytokine B10
  • NCBI_Gene: 3627
  • UniProtKB: P02778

Human CXCL10 Predicted Functions

Enables chemoattractant activity; chemokine receptor binding activity; and heparin binding activity. Involved in several processes, including positive regulation of release of sequestered calcium ion into cytosol; regulation of leukocyte chemotaxis; and response to virus. Acts upstream of or within cellular response to lipopolysaccharide and positive regulation of T cell migration. Located in extracellular region. Implicated in hepatitis B and middle cerebral artery infarction. Biomarker of several diseases, including artery disease (multiple); diabetes mellitus (multiple); fatty liver disease (multiple); liver disease (multiple); and lung disease (multiple).

Mouse Cxcl10 Target Information

Mouse Cxcl10 Predicted Functions

Predicted to enable chemoattractant activity; chemokine receptor binding activity; and heparin binding activity. Acts upstream of or within several processes, including defense response to virus; negative regulation of myoblast differentiation; and negative regulation of myoblast fusion. Located in external side of plasma membrane and extracellular space. Is expressed in several structures, including alimentary system; axial skeleton; hemolymphoid system; and liver. Human ortholog(s) of this gene implicated in hepatitis B; middle cerebral artery infarction; and type 1 diabetes mellitus. Orthologous to human CXCL10 (C-X-C motif chemokine ligand 10).

Rat Cxcl10 Target Information

  • Target Symbol: Cxcl10, C-X-C motif chemokine ligand 10
  • Alias:
    • 10 kDa interferon gamma-induced protein
    • C-X-C motif chemokine 10
    • chemokine (C-X-C motif) ligand 10
    • gamma-IP10
    • interferon-inducible cytokine IP-10
    • interferon-inducible protein 10
    • IP-10
    • protein Mob-1
    • Scyb10
    • small inducible cytokine B subfamily (Cys-X-Cys) member 10
    • small inducible cytokine B subfamily (Cys-X-Cys), member 10
    • small-inducible cytokine B10
  • NCBI_Gene: 245920
  • UniProtKB: P48973

Rat Cxcl10 Predicted Functions

Enables chemokine activity. Involved in several processes, including response to auditory stimulus; response to gamma radiation; and response to vitamin D. Located in extracellular space. Used to study adult respiratory distress syndrome; myocarditis; proteinuria; renovascular hypertension; and type 1 diabetes mellitus. Biomarker of brain ischemia; encephalitis; and uveitis. Human ortholog(s) of this gene implicated in hepatitis B and middle cerebral artery infarction. Orthologous to human CXCL10 (C-X-C motif chemokine ligand 10).

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