Powered by BiozEasyGo!™ Mouse ErbB3/HER3 One-Step ELISA Kit
$349.00 – $499.00
ELISA Kit Detail Information
| Related Target | |
|---|---|
| Species | mouse |
| Sample Type | Serum, plasma, cell culture supernatant, and other biological samples |
| Sample Volume | 10uL |
| Sensitivity | 2.18 pg/ml |
| Array Range | 23.44-1500pg/ml |
| Assay Time | 90min |
| Recovery | 70%-130% |
| Average Recovery | / |
| Intra Precision | < 10% |
| Inter Precision | < 10% |
| Plate | Detachable 96-well Plate |
| Storage | 2-8℃ |
| Delivery | blue ice |
| Components | Coated Microplate standard Assay Buffer (10×) TMB Stop Solution Washing Buffer (20×) |
| Assay Principle | This assay employs the quantitative sandwich enzyme immunoassay technique. A monoclonal antibody specific for Mouse IL-18 has been immobilized onto microwells, and one pellet of the HRP-linked detect antibody specific for IL-18 (light yellow) is pre-placed in the microwells, sealed by the adhesive film. Standard or samples are pipetted into the wells, then IL-18 present is bound by the immobilized antibody and detect antibody in the incubation. After washing, substrate solution reacts with HRP and color develops in proportion to the amount of IL-18 bound by the immobilized antibody. The color development is stopped and the intensity of the color is measured by microplate reader. |
Related Targets
ERBB3
ERBB3 Target Infomation Overview
- Target Symbol: ERBB3, erb-b2 receptor tyrosine kinase 3
- Gene Groups: Erb-b2 receptor tyrosine kinases
- Alias: LCCS2; HER3; HER-3
- Alias Names: lethal congenital contracture syndrome 2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3; human epidermal growth factor receptor 3
ERBB3, erb-b2 receptor tyrosine kinase 3 Target Infomation by Species
- Human
- Mouse
- Rat
Human ERBB3 Target Information
- Target Symbol: ERBB3, erb-b2 receptor tyrosine kinase 3
- Alias:
- avian erythroblastosis oncogene b 3
- c-erbB-3
- c-erbB3
- ErbB-3
- erbB3-S
- FERLK
- HER3
- human epidermal growth factor receptor 3
- LCCS2
- MDA-BF-1
- MGC88033
- p180-ErbB3
- p45-sErbB3
- p85-sErbB3
- proto-oncogene-like protein c-ErbB-3
- receptor tyrosine-protein kinase erbB-3
- tyrosine kinase-type cell surface receptor HER3
- v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
- VSCN1
- NCBI_Gene: 2065
- UniProtKB: P21860
Human Predicted Functions
Enables several functions, including ErbB-3 class receptor binding activity; neuregulin binding activity; and protein heterodimerization activity. Involved in several processes, including extrinsic apoptotic signaling pathway in absence of ligand; phosphatidylinositol 3-kinase signaling; and positive regulation of protein tyrosine kinase activity. Located in basolateral plasma membrane and extracellular space. Part of ERBB3:ERBB2 complex. Implicated in lethal congenital contracture syndrome 2; lung adenocarcinoma; lung non-small cell carcinoma; and neuronal intestinal dysplasia type A. Biomarker of carcinoma (multiple); ductal carcinoma in situ; prostate cancer; and urinary bladder cancer.
Mouse Erbb3 Target Information
- Target Symbol: Erbb3, erb-b2 receptor tyrosine kinase 3
- Alias:
- avian erythroblastosis oncogene B 3
- avian erythroblastosis oncogene B 3 receptor
- C76256
- Erbb-3
- Erbb3r
- expressed sequence C76256
- HER3
- nuc-ErbB3
- NCBI_Gene: 13867
Mouse Erbb3 Predicted Functions
Enables neuregulin receptor activity. Involved in ERBB2-ERBB3 signaling pathway; Schwann cell development; and myelination. Acts upstream of or within several processes, including negative regulation of motor neuron apoptotic process; nervous system development; and positive regulation of calcineurin-NFAT signaling cascade. Located in apical plasma membrane and lateral plasma membrane. Is active in plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and sensory organ epithelium. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 2; lung adenocarcinoma; lung non-small cell carcinoma; and neuronal intestinal dysplasia type A. Orthologous to human ERBB3 (erb-b2 receptor tyrosine kinase 3).
Rat Erbb3 Target Information
- Target Symbol: Erbb3, erb-b2 receptor tyrosine kinase 3
- Alias:
- avian erythroblastosis oncogene B 3
- c-erbB-3
- c-erbB3
- nuc-ErbB3
- proto-oncogene-like protein c-ErbB-3
- receptor tyrosine-protein kinase erbB-3
- v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
- v-erb-b2 erythroblastic leukemia viral oncogene homolog 3
- v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
- NCBI_Gene: 29496
- UniProtKB: Q62799
Rat Erbb3 Predicted Functions
Enables neuregulin binding activity and neuregulin receptor activity. Involved in several processes, including cellular response to mechanical stimulus; mammary gland involution; and positive regulation of D-glucose import. Located in neuronal cell body and postsynaptic membrane. Biomarker of amblyopia; chronic obstructive pulmonary disease; and median neuropathy. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 2; lung adenocarcinoma; lung non-small cell carcinoma; and neuronal intestinal dysplasia type A. Orthologous to human ERBB3 (erb-b2 receptor tyrosine kinase 3).
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