Human TrKA/NTRK1 ELISA Kit

$299.00 – $419.00

Related Target	NTRK1
Species	human
Sample Type	Serum, plasma, cell culture supernatant and other biological samples
Sample Volume	Serum, plasma: 10 μL, cell culture supernatant: 100 μL
Sensitivity	20.02pg/mL
Array Range	0.16-10ng/mL
Assay Time	3.5 h
Recovery	80%-108%
Average Recovery	95%

SKU: EK1248 Category: ELISA Kit

ELISA Kit Detail Information

Related Target	NTRK1
Species	human
Sample Type	Serum, plasma, cell culture supernatant and other biological samples
Sample Volume	Serum, plasma: 10 μL, cell culture supernatant: 100 μL
Sensitivity	20.02pg/mL
Array Range	0.16-10ng/mL
Assay Time	3.5 h
Recovery	80%-108%
Average Recovery	95%
Intra Precision	5.4%-7.7%
Inter Precision	6.5%-8.8%
Plate	Detachable 96-well Plate
Storage	If the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard should be stored at -20℃, while the other components should be stored at 4℃.
Delivery	4℃ Blue Ice Transport
Components	96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-Human TrKA/NTRK1 monoclonal antibody Human TrKA/NTRK1 freeze-dried standard TrKA/NTRK1 detect Antibody Standard Diluent HRP-labeled streptavidin Assay Buffer(10×) Substrate TMB Stop Solution Washing Buffer(20×) Sealing Film
Assay Principle	This assay employs the quantitative sandwich enzyme immunoassay technique. A monoclonal antibody specific for human TrkA has been pre-coated onto a microplate. Standard, samples and HRP-linked detect antibody specific for TrkA are pipetted into the wells and TrkA present is bound by the immobilized antibody and detect antibody following incubation. After washing, substrate solution is added to the wells and color develops in proportion to the amount of TrkA bound in the initial step. The color development is stopped and the intensity of the color is measured.

Related Targets

NTRK1

NTRK1 Target Infomation Overview

Target Symbol: NTRK1, neurotrophic receptor tyrosine kinase 1
Gene Groups: Receptor tyrosine kinases; Immunoglobulin like domain containing
Alias: TRK; TRKA; MTC
Alias Names: neurotrophic tyrosine kinase, receptor, type 1; high affinity nerve growth factor receptor; tropomyosin receptor kinase A

NTRK1, neurotrophic receptor tyrosine kinase 1 Target Infomation by Species

Human
Mouse
Rat

Human NTRK1 Target Information

Target Symbol: NTRK1, neurotrophic receptor tyrosine kinase 1
Alias:
- DKFZp781I14186
- gp140trk
- high affinity nerve growth factor receptor
- MTC
- neurotrophic tyrosine kinase, receptor, type 1
- Oncogene TRK
- p140-TrkA
- TRK
- trk precursor
- Trk-A
- TRK1
- TRK1-transforming tyrosine kinase protein
- TRKA
- tropomyosin receptor kinase A
- tropomyosin-related kinase A
- tyrosine kinase receptor A
NCBI_Gene: 4914
UniProtKB: P04629

Human NTRK1 Predicted Functions

Enables several functions, including nerve growth factor binding activity; nerve growth factor receptor activity; and protein homodimerization activity. Involved in several processes, including neurotrophin signaling pathway; positive regulation of intracellular signal transduction; and protein phosphorylation. Acts upstream of or within neuron projection development and peptidyl-tyrosine autophosphorylation. Located in plasma membrane. Part of receptor complex. Implicated in Alzheimer's disease; hereditary sensory neuropathy; hereditary sensory neuropathy type 4; and schizophrenia. Biomarker of several diseases, including Hirschsprung's disease; lung disease (multiple); neuroblastoma; obstructive sleep apnea; and rhinitis.

Mouse Ntrk1 Target Information

Target Symbol: Ntrk1, neurotrophic tyrosine kinase, receptor, type 1
Alias:
- C80751
- expressed sequence C80751
- Tkr
- Trk
- TrkA
- tyrosine kinase receptor proto-oncogene
NCBI_Gene: 18211
- UniprotKB: Q3UFB7

Mouse Ntrk1 Predicted Functions

Predicted to enable several functions, including GPI-linked ephrin receptor activity; nerve growth factor binding activity; and nerve growth factor receptor activity. Involved in circadian rhythm; negative regulation of neuron apoptotic process; and nervous system development. Acts upstream of or within several processes, including behavioral response to formalin induced pain; nerve growth factor signaling pathway; and nervous system development. Located in axon; cell surface; and endosome. Part of protein-containing complex. Is expressed in several structures, including branchial arch; nervous system; reproductive system; sensory organ; and trunk. Used to study hereditary sensory neuropathy. Human ortholog(s) of this gene implicated in Alzheimer's disease; hereditary sensory neuropathy; hereditary sensory neuropathy type 4; and schizophrenia. Orthologous to human NTRK1 (neurotrophic receptor tyrosine kinase 1).

Rat Ntrk1 Target Information

Target Symbol: Ntrk1, neurotrophic receptor tyrosine kinase 1
Alias:
- high affinity nerve growth factor receptor
- neurotrophic tyrosine kinase, receptor, type 1
- p140-TrkA
- slow nerve growth factor receptor
- Trk
- trk precursor
- trk-A
- TrkA neurotrophin receptor
- trkA proto-oncogene receptor
- tropomyosin-related kinase A
NCBI_Gene: 59109
- UniprotKB: P35739

Rat Ntrk1 Predicted Functions

Enables several functions, including GPI-linked ephrin receptor activity; nerve growth factor binding activity; and neurotrophin p75 receptor binding activity. Involved in several processes, including detection of stimulus involved in sensory perception of pain; nervous system development; and positive regulation of cell communication. Acts upstream of or within cellular response to growth factor stimulus and protein autophosphorylation. Located in several cellular components, including cell surface; endosome; and neuronal cell body. Part of protein-containing complex. Used to study Parkinsonism; glaucoma; and myofascial pain syndrome. Biomarker of several diseases, including colitis; diabetic neuropathy; glaucoma; periodontitis; and retinal detachment. Human ortholog(s) of this gene implicated in Alzheimer's disease; hereditary sensory neuropathy; hereditary sensory neuropathy type 4; and schizophrenia. Orthologous to human NTRK1 (neurotrophic receptor tyrosine kinase 1).

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