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Human TIM-1/KIM-1/HAVCR ELISA Kit
$350.00 – $450.00
| Sample Type | Serum, plasma, cell culture supernatant, and other biological samples |
|---|---|
| Sample Volume | 20 μL |
| Sensitivity | 1.42 pg/mL |
| Range | 31.25 pg/mL – 2000 pg/mL |
| Assay Time | 3.5 h |
| Recovery | 83% – 117% |
| Average Recovery | 1.02 |
| Intra Precision | 4.1% – 4.2% |
| Inter-Precision | 3.6% – 6.6% |
| Platform | ELISA |
| Plate | Detachable 96-well plate |
| Size | 96T/48T |
| Storage | If the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard solution should be stored at -20℃, while the other components should be stored at 4℃. |
| Delivery | 4℃ blue ice transportation |
| Components | 96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-TIM-1/KIM-1/HAVCR monoclonal antibody Human TIM-1/KIM-1/HAVCR freeze-dried standard TIM-1/KIM-1/HAVCR detect Antibody Standard Diluent Assay Buffer(10×) Substrate TMB Stop Solution Washing Buffer(20×) Sealing Film |
| Assay Principle | This kit utilizes the double antibody sandwich enzyme-linked immunosorbent assay (ELISA) detection technique.Specific anti-human TIM-1 antibodies are precoated on a high-affinity ELISA plate. Standard samples, test samples, and biotinylated detection antibodies are added to the wells of the ELISA plate. After incubation, TIM-1 present in the samples binds to the solid-phase antibodies and the detection antibodies. After washing to remove unbound substances, streptavidin-HRP labeled with horseradish peroxidase is added. After washing, a colorimetric substrate, TMB, is added and the plate is incubated in the dark for color development. The intensity of the color reaction is directly proportional to the concentration of TIM-1 in the samples.A stop solution is added to terminate the reaction, and the absorbance value is measured at a wavelength of 450 nm (with a reference wavelength range of 570-630 nm). |
Targets
HAVCR1
HAVCR1 Target Infomation Overview
- Target Symbol: HAVCR1, hepatitis A virus cellular receptor 1
- Gene Groups: CD molecules; V-set domain containing
- Alias: HAVCR-1; TIM-1; TIM1; HAVCR; TIMD1; CD365; KIM1
- Alias Names: T-cell immunoglobulin mucin family member 1; kidney injury molecule 1
HAVCR1, hepatitis A virus cellular receptor 1 Target Infomation by Species
HumanMouseRat
Human HAVCR1 Target Information
- Target Symbol: HAVCR1, hepatitis A virus cellular receptor 1
- Alias:
- CD365
- HAVCR
- HAVCR-1
- kidney injury molecule 1
- KIM-1
- KIM1
- T cell immunoglobin domain and mucin domain protein 1
- T-cell immunoglobulin mucin family member 1
- T-cell immunoglobulin mucin receptor 1
- T-cell membrane protein 1
- TIM
- TIM-1
- TIM1
- TIMD-1
- TIMD1
- NCBI_Gene: 26762
- UniProtKB: Q96D42
Human HAVCR1 Predicted Functions
Enables virus receptor activity. Predicted to be involved in phagocytosis, engulfment and positive regulation of mast cell activation. Predicted to act upstream of or within response to lipopolysaccharide and response to wounding. Part of motile cilium. Implicated in atopic dermatitis. Biomarker of several diseases, including hydronephrosis; hyperuricemia; kidney disease (multiple); relapsing-remitting multiple sclerosis; and vesicoureteral reflux.
Mouse Havcr1 Target Information
- Target Symbol: Havcr1, hepatitis A virus cellular receptor 1
- Alias:
- AI503787
- expressed sequence AI503787
- KIM-1
- T-cell immunoglobulin and mucin domain containing 1
- TIM-1
- Tim1
- Timd1
- NCBI_Gene: 171283
Mouse Havcr1 Predicted Functions
Enables phosphatidylserine binding activity. Acts upstream of or within positive regulation of mast cell activation; response to lipopolysaccharide; and response to wounding. Located in brush border and cell surface. Is expressed in brain; dorsal aorta; liver; lung; and reproductive system. Human ortholog(s) of this gene implicated in atopic dermatitis. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1).
Rat Havcr1 Target Information
- Target Symbol: Havcr1, hepatitis A virus cellular receptor 1
- Alias:
- HAVcr-1
- hepatitis A virus cellular receptor 1 homolog
- kidney injury molecule 1
- KIM-1
- Kim1
- t cell immunoglobulin and mucin domain-containing protein 1
- TIMD-1
- NCBI_Gene: 286934
Rat Havcr1 Predicted Functions
Predicted to enable phosphatidylserine binding activity and virus receptor activity. Involved in several processes, including phagocytosis, engulfment; response to mycotoxin; and response to testosterone. Located in several cellular components, including apical plasma membrane; cell surface; and phagocytic vesicle. Biomarker of colitis; hypertension; kidney failure (multiple); and proteinuria (multiple). Human ortholog(s) of this gene implicated in atopic dermatitis. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1).
