Human TIM-1/KIM-1/HAVCR ELISA Kit

$350.00$450.00

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TARGETSHAVCR1
SPECIESHuman
Sample TypeSerum, plasma, cell culture supernatant, and other biological samples
Sample Volume20 μL
Sensitivity1.42 pg/mL
Range31.25 pg/mL – 2000 pg/mL
Assay Time3.5 h
Recovery83% – 117%
Average Recovery1.02
Sample TypeSerum, plasma, cell culture supernatant, and other biological samples
Sample Volume20 μL
Sensitivity1.42 pg/mL
Range31.25 pg/mL – 2000 pg/mL
Assay Time3.5 h
Recovery83% – 117%
Average Recovery1.02
Intra Precision4.1% – 4.2%
Inter-Precision3.6% – 6.6%
PlatformELISA
PlateDetachable 96-well plate
Size96T/48T
StorageIf the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard solution should be stored at -20℃, while the other components should be stored at 4℃.
Delivery4℃ blue ice transportation
Components96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-TIM-1/KIM-1/HAVCR monoclonal antibody
Human TIM-1/KIM-1/HAVCR freeze-dried standard
TIM-1/KIM-1/HAVCR detect Antibody
Standard Diluent
Assay Buffer(10×)
Substrate TMB
Stop Solution
Washing Buffer(20×)
Sealing Film
Assay PrincipleThis kit utilizes the double antibody sandwich enzyme-linked immunosorbent assay (ELISA) detection technique.Specific anti-human TIM-1 antibodies are precoated on a high-affinity ELISA plate. Standard samples, test samples, and biotinylated detection antibodies are added to the wells of the ELISA plate. After incubation, TIM-1 present in the samples binds to the solid-phase antibodies and the detection antibodies. After washing to remove unbound substances, streptavidin-HRP labeled with horseradish peroxidase is added. After washing, a colorimetric substrate, TMB, is added and the plate is incubated in the dark for color development. The intensity of the color reaction is directly proportional to the concentration of TIM-1 in the samples.A stop solution is added to terminate the reaction, and the absorbance value is measured at a wavelength of 450 nm (with a reference wavelength range of 570-630 nm).

 

Targets

HAVCR1

HAVCR1 Target Infomation Overview

  • Target Symbol: HAVCR1, hepatitis A virus cellular receptor 1
  • Gene Groups: CD molecules; V-set domain containing
  • Alias: HAVCR-1; TIM-1; TIM1; HAVCR; TIMD1; CD365; KIM1
  • Alias Names: T-cell immunoglobulin mucin family member 1; kidney injury molecule 1

HAVCR1, hepatitis A virus cellular receptor 1 Target Infomation by Species

HumanMouseRat

Human HAVCR1 Target Information

  • Target Symbol: HAVCR1, hepatitis A virus cellular receptor 1
  • Alias:
    • CD365
    • HAVCR
    • HAVCR-1
    • kidney injury molecule 1
    • KIM-1
    • KIM1
    • T cell immunoglobin domain and mucin domain protein 1
    • T-cell immunoglobulin mucin family member 1
    • T-cell immunoglobulin mucin receptor 1
    • T-cell membrane protein 1
    • TIM
    • TIM-1
    • TIM1
    • TIMD-1
    • TIMD1
  • NCBI_Gene: 26762
  • UniProtKB: Q96D42

Human HAVCR1 Predicted Functions

Enables virus receptor activity. Predicted to be involved in phagocytosis, engulfment and positive regulation of mast cell activation. Predicted to act upstream of or within response to lipopolysaccharide and response to wounding. Part of motile cilium. Implicated in atopic dermatitis. Biomarker of several diseases, including hydronephrosis; hyperuricemia; kidney disease (multiple); relapsing-remitting multiple sclerosis; and vesicoureteral reflux.

Mouse Havcr1 Target Information

Mouse Havcr1 Predicted Functions

Enables phosphatidylserine binding activity. Acts upstream of or within positive regulation of mast cell activation; response to lipopolysaccharide; and response to wounding. Located in brush border and cell surface. Is expressed in brain; dorsal aorta; liver; lung; and reproductive system. Human ortholog(s) of this gene implicated in atopic dermatitis. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1).

Rat Havcr1 Target Information

  • Target Symbol: Havcr1, hepatitis A virus cellular receptor 1
  • Alias:
    • HAVcr-1
    • hepatitis A virus cellular receptor 1 homolog
    • kidney injury molecule 1
    • KIM-1
    • Kim1
    • t cell immunoglobulin and mucin domain-containing protein 1
    • TIMD-1
  • NCBI_Gene: 286934

Rat Havcr1 Predicted Functions

Predicted to enable phosphatidylserine binding activity and virus receptor activity. Involved in several processes, including phagocytosis, engulfment; response to mycotoxin; and response to testosterone. Located in several cellular components, including apical plasma membrane; cell surface; and phagocytic vesicle. Biomarker of colitis; hypertension; kidney failure (multiple); and proteinuria (multiple). Human ortholog(s) of this gene implicated in atopic dermatitis. Orthologous to human HAVCR1 (hepatitis A virus cellular receptor 1).

HAVCR1 Target News

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