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Human TrkB/NTRK2 ELISA Kit
$350.00 – $450.00
| Sample Type | Serum, plasma, cell culture supernatant, and other biological samples |
|---|---|
| Sample Volume | 100 μL |
| Sensitivity | 0.80 pg/mL |
| Range | 15.63 pg/mL – 1000 pg/mL |
| Assay Time | 3.5 h |
| Recovery | 88% – 112% |
| Average Recovery | 0.97 |
| Intra Precision | 1.9% – 3.0% |
| Inter-Precision | 3.3% – 3.6% |
| Platform | ELISA |
| Plate | Detachable 96-well plate |
| Size | 96T/48T |
| Storage | If the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard solution should be stored at -20℃, while the other components should be stored at 4℃. |
| Delivery | 4℃ blue ice transportation |
| Components | 96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-TrkB/NTRK2 monoclonal antibody Human TrkB/NTRK2 freeze-dried standard Human TrkB/NTRK2 detect Antibody Standard Diluent Assay Buffer(10×) Substrate TMB Stop Solution Washing Buffer(20×) Sealing Film |
| Assay Principle | This kit utilizes the double antibody sandwich enzyme-linked immunosorbent assay (ELISA) detection technique.Specific anti-human TrkB antibodies are precoated on a high-affinity ELISA plate. Standard samples, test samples, and the detection antibody labeled with horseradish peroxidase are added to the wells of the ELISA plate. After incubation, TrkB present in the samples binds to the solid-phase antibodies and the detection antibodies. After washing, a colorimetric substrate, TMB, is added and the plate is incubated in the dark for color development. The intensity of the color reaction is directly proportional to the concentration of TrkB in the samples. A stop solution is added to terminate the reaction, and the absorbance value is measured at a wavelength of 450 nm (with a reference wavelength range of 570-630 nm). |
Targets
NTRK2
NTRK2 Target Infomation Overview
- Target Symbol: NTRK2, neurotrophic receptor tyrosine kinase 2
- Gene Groups: Receptor tyrosine kinases; I-set domain containing
- Alias: TRKB
- Alias Names: BDNF/NT-3 growth factors receptor; neurotrophic tyrosine kinase, receptor, type 2
NTRK2, neurotrophic receptor tyrosine kinase 2 Target Infomation by Species
HumanMouseRat
Human NTRK2 Target Information
- Target Symbol: NTRK2, neurotrophic receptor tyrosine kinase 2
- Alias:
- BDNF-tropomyosine receptor kinase B
- BDNF/NT-3 growth factors receptor
- DEE58
- EIEE58
- GP145-TrkB
- neurotrophic tyrosine kinase receptor type 2
- neurotrophic tyrosine kinase, receptor, type 2
- neurotrophic tyrosine receptor kinase type 2
- OBHD
- trk-B
- TRKB
- trkB tyrosine kinase
- tropomyosin-related kinase B
- tyrosine kinase receptor B
- NCBI_Gene: 4915
- UniProtKB: Q16620
Human NTRK2 Predicted Functions
Enables brain-derived neurotrophic factor-activated receptor activity; neurotrophin binding activity; and protease binding activity. Involved in brain-derived neurotrophic factor receptor signaling pathway. Acts upstream of or within negative regulation of amyloid-beta formation. Is integral component of plasma membrane. Part of receptor complex. Implicated in Alzheimer’s disease; autistic disorder; developmental and epileptic encephalopathy 58; major depressive disorder; and morbid obesity. Biomarker of bipolar disorder; idiopathic pulmonary fibrosis; major depressive disorder; and schizophrenia.
Mouse Ntrk2 Target Information
- Target Symbol: Ntrk2, neurotrophic tyrosine kinase, receptor, type 2
- Alias:
- AI848316
- C030027L06Rik
- expressed sequence AI848316
- RIKEN cDNA C030027L06 gene
- Tkrb
- trkB
- tyrosine protein kinase receptor
- NCBI_Gene: 18212
Mouse Ntrk2 Predicted Functions
Enables brain-derived neurotrophic factor binding activity and brain-derived neurotrophic factor-activated receptor activity. Involved in several processes, including brain-derived neurotrophic factor receptor signaling pathway; nervous system development; and trans-synaptic signaling, modulating synaptic transmission. Acts upstream of or within several processes, including neurogenesis; neuronal action potential propagation; and positive regulation of peptidyl-serine phosphorylation. Located in several cellular components, including early endosome; postsynaptic density; and postsynaptic membrane. Is expressed in several structures, including alimentary system; cardiovascular system; future brain; genitourinary system; and nervous system. Human ortholog(s) of this gene implicated in Alzheimer’s disease; autistic disorder; developmental and epileptic encephalopathy 58; major depressive disorder; and morbid obesity. Orthologous to human NTRK2 (neurotrophic receptor tyrosine kinase 2).
Rat Ntrk2 Target Information
- Target Symbol: Ntrk2, neurotrophic receptor tyrosine kinase 2
- Alias:
- BDNF/NT-3 growth factors receptor
- GP145-TrkB/GP95-TrkB
- Neural receptor protein-tyrosine kinase (trkB)
- neurotrophic tyrosine kinase, receptor, type 2
- neurotrophic tyrosine receptor kinase type 2
- RATTRKB1
- Tkrb
- trk-B
- trkB
- trkB tyrosine kinase
- TRKB1
- NCBI_Gene: 25054
Rat Ntrk2 Predicted Functions
Enables several functions, including brain-derived neurotrophic factor binding activity; brain-derived neurotrophic factor-activated receptor activity; and protein homodimerization activity. Involved in several processes, including brain-derived neurotrophic factor receptor signaling pathway; positive regulation of cell communication; and regulation of neuron projection development. Acts upstream of or within positive regulation of glucocorticoid receptor signaling pathway. Located in several cellular components, including distal axon; perikaryon; and postsynaptic density. Is integral component of plasma membrane. Is active in glutamatergic synapse and postsynapse. Used to study glaucoma. Biomarker of several diseases, including attention deficit hyperactivity disorder; colitis; mental depression; post-traumatic stress disorder; and temporal lobe epilepsy. Human ortholog(s) of this gene implicated in Alzheimer’s disease; autistic disorder; developmental and epileptic encephalopathy 58; major depressive disorder; and morbid obesity. Orthologous to human NTRK2 (neurotrophic receptor tyrosine kinase 2).
