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Mouse IL-6Rα ELISA Kit
$350.00 – $450.00
| Sample Type | Serum, plasma, cell culture supernatant, and other biological samples |
|---|---|
| Sample Volume | 100 μL(diluent) |
| Sensitivity | 3.71 pg/mL |
| Range | 125 pg/mL – 8000 pg/mL |
| Assay Time | 3.5 h |
| Recovery | 89% – 112% |
| Average Recovery | 0.98 |
| Intra Precision | 1.5% – 4.4% |
| Inter-Precision | 1.3%-4.2% |
| Platform | ELISA |
| Plate | Detachable 96-well plate |
| Size | 96T/48T |
| Storage | If the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard solution should be stored at -20℃, while the other components should be stored at 4℃. |
| Delivery | 4℃ blue ice transportation |
| Components | 96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-IL-6Rα monoclonal antibody Mouse IL-6Rα freeze-dried standard IL-6Rα detect Antibody Standard Diluent Assay Buffer(10×) Substrate TMB Stop Solution Washing Buffer(20×) Sealing Film |
| Assay Principle | This kit utilizes the double antibody sandwich enzyme-linked immunosorbent assay (ELISA) detection technique.Specific anti-mouse IL-6Rα antibodies are precoated on a high-affinity ELISA plate. Standard samples, test samples, and biotinylated detection antibodies are added to the wells of the ELISA plate. After incubation, IL-6Rα present in the samples binds to the solid-phase antibodies and the detection antibodies. After washing to remove unbound substances, streptavidin-HRP labeled with horseradish peroxidase is added. After washing, a colorimetric substrate, TMB, is added and the plate is incubated in the dark for color development. The intensity of the color reaction is directly proportional to the concentration of IL-6Rα in the samples.A stop solution is added to terminate the reaction, and the absorbance value is measured at a wavelength of 450 nm (with a reference wavelength range of 570-630 nm). |
Targets
IL6R
IL6R Target Infomation Overview
- Target Symbol: IL6R, interleukin 6 receptor
- Gene Groups: CD molecules; Immunoglobulin like domain containing; Interleukin receptors
- Alias: CD126; IL-6R; IL-1Ra; IL6RA; gp80
- Alias Names: membrane glycoprotein 80; interleukin 6 receptor subunit alpha
IL6R, interleukin 6 receptor Target Infomation by Species
HumanMouseRat
Human IL6R Target Information
- Target Symbol: IL6R, interleukin 6 receptor
- Alias:
- CD126
- CD126 antigen
- gp80
- HIES5
- IL-1Ra
- IL-6 receptor subunit alpha
- IL-6R
- IL-6R 1
- IL-6R subunit alpha
- IL-6R-1
- IL-6R-alpha
- IL-6RA
- IL6Q
- IL6QTL
- IL6RA
- IL6RQ
- interleukin 6 receptor alpha subunit
- interleukin-6 receptor subunit alpha
- membrane glycoprotein 80
- MGC104991
- NCBI_Gene: 3570
- UniProtKB: P08887
Human IL6R Predicted Functions
Enables cytokine binding activity; enzyme binding activity; and protein homodimerization activity. Contributes to ciliary neurotrophic factor receptor activity; interleukin-6 receptor activity; and interleukin-6 receptor binding activity. Involved in several processes, including cytokine-mediated signaling pathway; positive regulation of cell population proliferation; and positive regulation of macromolecule metabolic process. Located in apical plasma membrane and extracellular space. Part of ciliary neurotrophic factor receptor complex and interleukin-6 receptor complex. Implicated in Alzheimer’s disease; Huntington’s disease; hyper IgE syndrome; obesity; and stomach cancer. Biomarker of several diseases, including Graves’ disease; obesity; proliferative diabetic retinopathy; pulmonary tuberculosis; and sleep apnea.
Mouse Il6ra Target Information
- Target Symbol: Il6ra, interleukin 6 receptor, alpha
- Alias:
- CD126
- IL-6 receptor alpha chain
- IL-6R
- Il6r
- interleukin 6 receptor
- NCBI_Gene: 16194
Mouse Il6ra Predicted Functions
Enables interleukin-6 binding activity and interleukin-6 receptor activity. Involved in T-helper 17 cell lineage commitment and interleukin-6-mediated signaling pathway. Located in cell surface. Part of interleukin-6 receptor complex. Is expressed in several structures, including adipose tissue; alimentary system; genitourinary system; hemolymphoid system; and nervous system. Human ortholog(s) of this gene implicated in Alzheimer’s disease; Huntington’s disease; hyper IgE syndrome; obesity; and stomach cancer. Orthologous to human IL6R (interleukin 6 receptor).
Rat Il6r Target Information
- Target Symbol: Il6r, interleukin 6 receptor
- Alias:
- IL-6 receptor subunit alpha
- IL-6R 1
- IL-6R subunit alpha
- IL-6R-alpha
- IL-6RA
- IL6R1
- Il6ra
- interleukin 6 receptor, alpha
- interleukin-6 receptor subunit alpha
- NCBI_Gene: 24499
Rat Il6r Predicted Functions
Predicted to enable several functions, including cytokine binding activity; cytokine receptor activity; and protein homodimerization activity. Predicted to contribute to ciliary neurotrophic factor receptor activity and interleukin-6 receptor binding activity. Involved in several processes, including response to cAMP; response to gamma radiation; and response to lipopolysaccharide. Located in extracellular space and neuronal cell body membrane. Biomarker of several diseases, including congestive heart failure; mental depression; orchitis; sciatic neuropathy; and visual epilepsy. Human ortholog(s) of this gene implicated in Alzheimer’s disease; Huntington’s disease; hyper IgE syndrome; obesity; and stomach cancer. Orthologous to human IL6R (interleukin 6 receptor).
